Curated insights • How it Works • Practical Pearls • Evidence Base
Intended for adult patients with paroxysmal, persistent, or permanent AF. It is the gold-standard tool for both the ACC/AHA and ESC guidelines.
| C — Congestive Heart Failure |
| H — Hypertension |
| A2 — Age ≥ 75 years |
| D — Diabetes Mellitus |
| S2 — Stroke History |
| V — Vascular Disease |
| A — Age 65–74 years |
| Sc — Sex Category (Female) |
| Score 0 |
| Score 1 |
| Score 2 |
| Score 3 |
| Score 4 |
| Score 5 |
| Score 6 |
The score quantifies factors that contribute to Virchow’s Triad in the left atrium: stasis (HF), endothelial injury (HTN, Diabetes), and hypercoagulability (Age, Vascular disease).
Direct Oral Anticoagulants (DOACs) like Apixaban or Rivaroxaban are preferred over Warfarin unless moderate-severe mitral stenosis or a mechanical valve is present.
Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach.
Evaluation of risk stratification schemes for ischaemic stroke and bleeding in 182,678 patients with atrial fibrillation: the Swedish Atrial Fibrillation cohort study.
The CHA2DS2-VASc score was developed as an evolution of the simpler CHADS2 score. The original CHADS2 left many patients in a "grey zone" of intermediate risk. By refining the age brackets and adding vascular/sex variables, Gregory Lip and colleagues aimed to clarify who truly benefits from OAC.
A world-renowned expert in AF from the University of Liverpool. His research has moved AF management toward a "risk-based" approach, emphasizing the importance of stroke prevention as the cornerstone of care.
CHA2DS2-VASc: Predicts stroke risk in patients with non-valvular Atrial Fibrillation.
Curated insights • How it Works • Practical Pearls • Evidence Base
Intended for adult patients with paroxysmal, persistent, or permanent AF. It is the gold-standard tool for both the ACC/AHA and ESC guidelines.
| C — Congestive Heart Failure |
| H — Hypertension |
| A2 — Age ≥ 75 years |
| D — Diabetes Mellitus |
| S2 — Stroke History |
| V — Vascular Disease |
| A — Age 65–74 years |
| Sc — Sex Category (Female) |
| Score 0 |
| Score 1 |
| Score 2 |
| Score 3 |
| Score 4 |
| Score 5 |
| Score 6 |
The score quantifies factors that contribute to Virchow’s Triad in the left atrium: stasis (HF), endothelial injury (HTN, Diabetes), and hypercoagulability (Age, Vascular disease).
Direct Oral Anticoagulants (DOACs) like Apixaban or Rivaroxaban are preferred over Warfarin unless moderate-severe mitral stenosis or a mechanical valve is present.
Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach.
Evaluation of risk stratification schemes for ischaemic stroke and bleeding in 182,678 patients with atrial fibrillation: the Swedish Atrial Fibrillation cohort study.
The CHA2DS2-VASc score was developed as an evolution of the simpler CHADS2 score. The original CHADS2 left many patients in a "grey zone" of intermediate risk. By refining the age brackets and adding vascular/sex variables, Gregory Lip and colleagues aimed to clarify who truly benefits from OAC.
A world-renowned expert in AF from the University of Liverpool. His research has moved AF management toward a "risk-based" approach, emphasizing the importance of stroke prevention as the cornerstone of care.
