Curated insights • How it Works • Practical Pearls • Evidence Base
The SHFM is a multivariable Cox proportional hazards model derived from several prospective randomized trials. It incorporates 24 variables to estimate the hazard ratio and absolute survival probability over 1, 2, and 5 years.
The model notably high-weights the dose of loop diuretics. While diuretics are necessary for symptom management, high doses are often markers of advanced refractory disease and neurohormonal activation, contributing strongly to the predicted hazard.
The SHFM is uniquely suited for patient counseling. By toggling "protective" entries like ACEi or BB, a clinician can show a patient the projected "years of life gained" by adherence to GDMT.
The Seattle Heart Failure Model: prediction of survival in heart failure.
Validation of the Seattle Heart Failure Model in a modern heart failure cohort.
Seattle Heart Failure Model: Multivariable tool to predict survival in heart failure. Incorporates labs, meds, and devices.