anticoagulant Registry

ANGIOMAX

Comprehensive clinical and safety monograph for ANGIOMAX (ANGIOMAX).

ANGIOMAX RTU

Comprehensive clinical and safety monograph for ANGIOMAX RTU (ANGIOMAX RTU).

APIXABAN

Strong dual inducers of CYP3A4 and P-gp (eg rifampin) decrease apixaban levels increasing stroke risk Risk of serious and fatal bleeding discontinue if active bleeding occurs.

ARIXTRA

Comprehensive clinical and safety monograph for ARIXTRA (ARIXTRA).

BEVYXXA

Comprehensive clinical and safety monograph for BEVYXXA (BEVYXXA).

CALCIPARINE

Comprehensive clinical and safety monograph for CALCIPARINE (CALCIPARINE).

COUMADIN

Comprehensive clinical and safety monograph for COUMADIN (COUMADIN).

DEFENCATH

Comprehensive clinical and safety monograph for DEFENCATH (DEFENCATH).

DICUMAROL

Comprehensive clinical and safety monograph for DICUMAROL (DICUMAROL).

EDOXABAN

Comprehensive clinical and safety monograph for EDOXABAN (EDOXABAN).

EMBLAVEO

Comprehensive clinical and safety monograph for EMBLAVEO (EMBLAVEO).

FONDAPARINUX SODIUM

Comprehensive clinical and safety monograph for FONDAPARINUX SODIUM (FONDAPARINUX SODIUM).

FRAGMIN

Comprehensive clinical and safety monograph for FRAGMIN (FRAGMIN).

HEDULIN

Comprehensive clinical and safety monograph for HEDULIN (HEDULIN).

Heparin (UFH)

Safe in pregnancy. Unfractionated heparin does not cross the placenta due to its large molecular size. Preferred over LMWH in specific scenarios: near delivery (allows complete reversal with protamine), in patients with renal impairment (where LMWH is less predictable), and for acute PE requiring thrombolysis or catheter-directed therapy. Requires aPTT monitoring. Long-term use associated with heparin-induced osteoporosis and thrombocytopenia (HIT); LMWH preferred for long-term use.

HEPARIN LOCK FLUSH

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 1,000 UNITS IN DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 10,000 UNITS AND DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 10,000 UNITS IN DEXTROSE 5%

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 10,000 UNITS IN DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 12,500 UNITS IN DEXTROSE 5%

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 12,500 UNITS IN DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 2,000 UNITS IN DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 20,000 UNITS AND DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 20,000 UNITS IN DEXTROSE 5%

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 20,000 UNITS IN DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 25,000 UNITS AND DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 25,000 UNITS IN DEXTROSE 5%

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 25,000 UNITS IN DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM 5,000 UNITS IN DEXTROSE 5% IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM IN PLASTIC CONTAINER

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

HEPARIN SODIUM PRESERVATIVE FREE

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

LIPO-HEPIN

Comprehensive clinical and safety monograph for LIPO-HEPIN (LIPO-HEPIN).

LIQUAEMIN LOCK FLUSH

Comprehensive clinical and safety monograph for LIQUAEMIN LOCK FLUSH (LIQUAEMIN LOCK FLUSH).

LIQUAEMIN SODIUM

Comprehensive clinical and safety monograph for LIQUAEMIN SODIUM (LIQUAEMIN SODIUM).

LIQUAEMIN SODIUM PRESERVATIVE FREE

Comprehensive clinical and safety monograph for LIQUAEMIN SODIUM PRESERVATIVE FREE (LIQUAEMIN SODIUM PRESERVATIVE FREE).

LIQUAMAR

Comprehensive clinical and safety monograph for LIQUAMAR (LIQUAMAR).

MIRADON

Comprehensive clinical and safety monograph for MIRADON (MIRADON).

ORGARAN

Comprehensive clinical and safety monograph for ORGARAN (ORGARAN).

PANHEPRIN

Comprehensive clinical and safety monograph for PANHEPRIN (PANHEPRIN).

PANWARFIN

Comprehensive clinical and safety monograph for PANWARFIN (PANWARFIN).

PRADAXA

Comprehensive clinical and safety monograph for PRADAXA (PRADAXA).

PRAXBIND

Comprehensive clinical and safety monograph for PRAXBIND (PRAXBIND).

RIVAROXABAN

Strong dual inducers of CYP3A4 and P-gp decrease levels increasing stroke risk Risk of serious and fatal bleeding discontinue if active bleeding occurs.

SAVAYSA

Comprehensive clinical and safety monograph for SAVAYSA (SAVAYSA).

SODIUM HEPARIN

Other drugs that affect hemostasis increase bleeding risk Can cause heparin-induced thrombocytopenia (HIT) and bleeding.

Warfarin

Contraindicated in most circumstances. Warfarin is a proven human teratogen. Exposure between 6–9 weeks gestation causes Fetal Warfarin Syndrome: nasal hypoplasia, stippled epiphyses, and limb defects in approximately 5% of exposed fetuses. Any trimester exposure carries risk of fetal intracranial hemorrhage due to anticoagulation of the fetal blood. Exception: women with mechanical heart valves may require warfarin due to inadequate LMWH valve protection — this requires individualized multidisciplinary decision-making.

WARFARIN SODIUM

A vast number of drugs can increase or decrease INR through various mechanisms Has a narrow therapeutic index and requires frequent INR monitoring to prevent bleeding or clotting.

XARELTO

Comprehensive clinical and safety monograph for XARELTO (XARELTO).