ABELCET Use only if clearly needed; amphotericin B is considered category B (no evidence of risk), but adequate human studies are lacking. Should be reserved for serious systemic infections where benefit outweighs potential fetal risk. | Polyene antifungal | caution |
AMBISOME Comprehensive clinical and safety monograph for AMBISOME (AMBISOME). | Antifungal | caution |
AMPHOTEC Comprehensive clinical and safety monograph for AMPHOTEC (AMPHOTEC). | Antifungal | caution |
AMPHOTERICIN B Comprehensive clinical and safety monograph for AMPHOTERICIN B (AMPHOTERICIN B). | Antifungal | caution |
ANCOBON Comprehensive clinical and safety monograph for ANCOBON (ANCOBON). | Antifungal | caution |
AUKELSO Comprehensive clinical and safety monograph for AUKELSO (AUKELSO). | Topical Antifungal | caution |
BUTENAFINE HYDROCHLORIDE Comprehensive clinical and safety monograph for BUTENAFINE HYDROCHLORIDE (BUTENAFINE HYDROCHLORIDE). | Antifungal | caution |
BUTOCONAZOLE NITRATE No significant drug interactions For vaginal use only not for ophthalmic or oral use. | Antifungal | safe |
CANCIDAS Comprehensive clinical and safety monograph for CANCIDAS (CANCIDAS). | Echinocandin Antifungal | caution |
CANDEX Comprehensive clinical and safety monograph for CANDEX (CANDEX). | Topical Antifungal and Corticosteroid | caution |
CASPOFUNGIN ACETATE Cyclosporine increases caspofungin exposure and may cause elevated liver enzymes Not for use in hepatic impairment. | Echinocandin Antifungal | safe |
CICLOPIROX No significant drug interactions For topical use only not for ophthalmic use. | Antifungal | safe |
CLOTRIMAZOLE No significant drug interactions For topical use only not for ophthalmic use. | Antifungal | safe |
CRESEMBA Comprehensive clinical and safety monograph for CRESEMBA (CRESEMBA). | Antifungal | caution |
DIFLUCAN Comprehensive clinical and safety monograph for DIFLUCAN (DIFLUCAN). | Antifungal | caution |
DIFLUCAN IN DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for DIFLUCAN IN DEXTROSE 5% IN PLASTIC CONTAINER (DIFLUCAN IN DEXTROSE 5% IN PLASTIC CONTAINER). | Antifungal | caution |
ECONAZOLE NITRATE No significant drug interactions For topical use only not for ophthalmic use. | Antifungal | safe |
ECOZA Comprehensive clinical and safety monograph for ECOZA (ECOZA). | Topical Antifungal | caution |
EFINACONAZOLE Comprehensive clinical and safety monograph for EFINACONAZOLE (EFINACONAZOLE). | Antifungal Agent | caution |
ERAXIS Comprehensive clinical and safety monograph for ERAXIS (ERAXIS). | Echinocandin Antifungal | caution |
ERMEZA Comprehensive clinical and safety monograph for ERMEZA (ERMEZA). | Topical Azole Antifungal | caution |
ERTACZO Comprehensive clinical and safety monograph for ERTACZO (ERTACZO). | Topical Azole Antifungal | caution |
EXELDERM Comprehensive clinical and safety monograph for EXELDERM (EXELDERM). | Topical Antifungal | caution |
EXSEL Comprehensive clinical and safety monograph for EXSEL (EXSEL). | Topical Antifungal | caution |
EXTINA Comprehensive clinical and safety monograph for EXTINA (EXTINA). | Antifungal | caution |
FEMSTAT Comprehensive clinical and safety monograph for FEMSTAT (FEMSTAT). | Antifungal | caution |
FEMSTAT 3 Comprehensive clinical and safety monograph for FEMSTAT 3 (FEMSTAT 3). | Antifungal | caution |
Fluconazole Oral fluconazole has a significant gestational-age-dependent risk profile. A single low dose (150 mg) for vaginal candidiasis is commonly used but increasingly scrutinized: a large 2016 Danish cohort (n=3,315) found a doubling of spontaneous abortion risk, and a 2020 NEJM study identified a significant association between single-dose and high-dose fluconazole use in T1 and cardiac septal defects. High-dose prolonged fluconazole (400–800 mg/day) is a known teratogen causing a distinctive skeletal malformation syndrome. Use topical azoles (clotrimazole, miconazole) as first-line for vaginal candidiasis. | Azole Antifungal | caution |
FLUCONAZOLE IN DEXTROSE 5% IN PLASTIC CONTAINER Inhibits CYP2C9 and CYP3A4 increasing levels of many drugs (eg warfarin phenytoin) Can cause QT prolongation and subsequent arrhythmias. | Azole Antifungal | safe |
FLUCYTOSINE Comprehensive clinical and safety monograph for FLUCYTOSINE (FLUCYTOSINE). | Antifungal Agent | caution |
FOCINVEZ Comprehensive clinical and safety monograph for FOCINVEZ (FOCINVEZ). | Antifungal | caution |
FULVICIN P/G Comprehensive clinical and safety monograph for FULVICIN P/G (FULVICIN P/G). | Antifungal | caution |
FULVICIN P/G 165 Comprehensive clinical and safety monograph for FULVICIN P/G 165 (FULVICIN P/G 165). | Antifungal | caution |
FULVICIN P/G 330 Comprehensive clinical and safety monograph for FULVICIN P/G 330 (FULVICIN P/G 330). | Antifungal | caution |
FULVICIN-U/F Comprehensive clinical and safety monograph for FULVICIN-U/F (FULVICIN-U/F). | Antifungal | caution |
FUNGIZONE Comprehensive clinical and safety monograph for FUNGIZONE (FUNGIZONE). | Antifungal | caution |
GERIMAL Comprehensive clinical and safety monograph for GERIMAL (GERIMAL). | Griseofulvin Antifungal | caution |
GRIFULVIN V Comprehensive clinical and safety monograph for GRIFULVIN V (GRIFULVIN V). | Antifungal | caution |
GRIS-PEG Comprehensive clinical and safety monograph for GRIS-PEG (GRIS-PEG). | Antifungal | caution |
GRISACTIN Comprehensive clinical and safety monograph for GRISACTIN (GRISACTIN). | Antifungal | caution |
GRISACTIN ULTRA Comprehensive clinical and safety monograph for GRISACTIN ULTRA (GRISACTIN ULTRA). | Antifungal | caution |
GRISEOFULVIN Warfarin metabolism is decreased increasing INR Can cause photosensitivity and lupus-like syndrome. | Antifungal | avoid |
GRISEOFULVIN, ULTRAMICROSIZE Warfarin metabolism is decreased increasing INR Can cause photosensitivity and lupus-like syndrome. | Antifungal | avoid |
GYNAZOLE-1 Comprehensive clinical and safety monograph for GYNAZOLE-1 (GYNAZOLE-1). | Azole Antifungal | caution |
GYNE-LOTRIMIN Comprehensive clinical and safety monograph for GYNE-LOTRIMIN (GYNE-LOTRIMIN). | Azole Antifungal | caution |
GYNE-LOTRIMIN 3 Comprehensive clinical and safety monograph for GYNE-LOTRIMIN 3 (GYNE-LOTRIMIN 3). | Azole Antifungal | caution |
GYNE-LOTRIMIN 3 COMBINATION PACK Comprehensive clinical and safety monograph for GYNE-LOTRIMIN 3 COMBINATION PACK (GYNE-LOTRIMIN 3 COMBINATION PACK). | Azole Antifungal | caution |
GYNE-LOTRIMIN COMBINATION PACK Comprehensive clinical and safety monograph for GYNE-LOTRIMIN COMBINATION PACK (GYNE-LOTRIMIN COMBINATION PACK). | Azole Antifungal | caution |
GYNIX Comprehensive clinical and safety monograph for GYNIX (GYNIX). | Polyene Antifungal | caution |
HALOTEX Comprehensive clinical and safety monograph for HALOTEX (HALOTEX). | Antifungal | caution |
HEAD & SHOULDERS CONDITIONER Comprehensive clinical and safety monograph for HEAD & SHOULDERS CONDITIONER (HEAD & SHOULDERS CONDITIONER). | Antifungal/Antidandruff | caution |
IMPEKLO Comprehensive clinical and safety monograph for IMPEKLO (IMPEKLO). | Antifungal | caution |
ITRACONAZOLE Inhibits CYP3A4 increasing levels of many drugs (eg statins) Contraindicated with drugs that prolong QT interval and can cause negative inotropy and heart failure. | Azole Antifungal | avoid |
JUBLIA Comprehensive clinical and safety monograph for JUBLIA (JUBLIA). | Antifungal - Triazole | caution |
KERYDIN Comprehensive clinical and safety monograph for KERYDIN (KERYDIN). | Antifungal | caution |
KETOCONAZOLE Strong CYP3A4 inhibitor that can significantly increase levels of many drugs (eg statins) Contraindicated due to risk of hepatotoxicity and adrenal insufficiency. | Azole Antifungal | caution |
KETOZOLE Comprehensive clinical and safety monograph for KETOZOLE (KETOZOLE). | Antifungal | caution |
LAMISIL Comprehensive clinical and safety monograph for LAMISIL (LAMISIL). | Antifungal | caution |
LAMISIL AT Comprehensive clinical and safety monograph for LAMISIL AT (LAMISIL AT). | Antifungal | caution |
LOPROX Comprehensive clinical and safety monograph for LOPROX (LOPROX). | Antifungal | caution |
LOTRIMIN Comprehensive clinical and safety monograph for LOTRIMIN (LOTRIMIN). | Topical Antifungal | caution |
LOTRIMIN AF Comprehensive clinical and safety monograph for LOTRIMIN AF (LOTRIMIN AF). | Topical Antifungal | caution |
LOTRIMIN ULTRA Comprehensive clinical and safety monograph for LOTRIMIN ULTRA (LOTRIMIN ULTRA). | Topical Antifungal | caution |
LOTRISONE Comprehensive clinical and safety monograph for LOTRISONE (LOTRISONE). | Topical Antifungal/Corticosteroid Combination | caution |
LUZU Comprehensive clinical and safety monograph for LUZU (LUZU). | Topical Antifungal | caution |
LYNOZYFIC Comprehensive clinical and safety monograph for LYNOZYFIC (LYNOZYFIC). | Antifungal | caution |
M-ZOLE 3 COMBINATION PACK Comprehensive clinical and safety monograph for M-ZOLE 3 COMBINATION PACK (M-ZOLE 3 COMBINATION PACK). | Antifungal | caution |
M-ZOLE 7 DUAL PACK Comprehensive clinical and safety monograph for M-ZOLE 7 DUAL PACK (M-ZOLE 7 DUAL PACK). | Antifungal | caution |
MENTAX Comprehensive clinical and safety monograph for MENTAX (MENTAX). | Topical Antifungal | caution |
MENTAX-TC Comprehensive clinical and safety monograph for MENTAX-TC (MENTAX-TC). | Topical Antifungal | caution |
MICAFUNGIN Comprehensive clinical and safety monograph for MICAFUNGIN (MICAFUNGIN). | Antifungal (Echinocandin) | caution |
MICAFUNGIN SODIUM Comprehensive clinical and safety monograph for MICAFUNGIN SODIUM (MICAFUNGIN SODIUM). | Antifungal (Echinocandin) | caution |
MICONAZOLE 3 Warfarin metabolism is inhibited increasing INR For topical use only not for ophthalmic use. | Antifungal | safe |
MICONAZOLE 3 COMBINATION PACK Warfarin metabolism is inhibited increasing INR For topical use only not for ophthalmic use. | Antifungal | safe |
MICONAZOLE 7 Warfarin metabolism is inhibited increasing INR For topical use only not for ophthalmic use. | Antifungal | safe |
MICONAZOLE 7 COMBINATION PACK Warfarin metabolism is inhibited increasing INR For topical use only not for ophthalmic use. | Antifungal | safe |
MICONAZOLE NITRATE Warfarin metabolism is inhibited increasing INR For topical use only not for ophthalmic use. | Antifungal | safe |
MICONAZOLE NITRATE COMBINATION PACK Warfarin metabolism is inhibited increasing INR For topical use only not for ophthalmic use. | Antifungal | safe |
MONISTAT Comprehensive clinical and safety monograph for MONISTAT (MONISTAT). | Antifungal | caution |
MONISTAT 1 COMBINATION PACK Comprehensive clinical and safety monograph for MONISTAT 1 COMBINATION PACK (MONISTAT 1 COMBINATION PACK). | Antifungal | caution |
MONISTAT 3 Comprehensive clinical and safety monograph for MONISTAT 3 (MONISTAT 3). | Antifungal | caution |
MONISTAT 3 COMBINATION PACK Comprehensive clinical and safety monograph for MONISTAT 3 COMBINATION PACK (MONISTAT 3 COMBINATION PACK). | Antifungal | caution |
MONISTAT 3 COMBINATION PACK (PREFILLED) Comprehensive clinical and safety monograph for MONISTAT 3 COMBINATION PACK (PREFILLED) (MONISTAT 3 COMBINATION PACK (PREFILLED)). | Antifungal | caution |
MONISTAT 5 Comprehensive clinical and safety monograph for MONISTAT 5 (MONISTAT 5). | Antifungal | caution |
MONISTAT 7 Comprehensive clinical and safety monograph for MONISTAT 7 (MONISTAT 7). | Antifungal | caution |
MONISTAT 7 COMBINATION PACK Comprehensive clinical and safety monograph for MONISTAT 7 COMBINATION PACK (MONISTAT 7 COMBINATION PACK). | Antifungal | caution |
MONISTAT DUAL- PAK Comprehensive clinical and safety monograph for MONISTAT DUAL- PAK (MONISTAT DUAL- PAK). | Antifungal | caution |
MONISTAT-DERM Comprehensive clinical and safety monograph for MONISTAT-DERM (MONISTAT-DERM). | Antifungal | caution |
MYCAMINE Comprehensive clinical and safety monograph for MYCAMINE (MYCAMINE). | Echinocandin Antifungal | caution |
MYCELEX Comprehensive clinical and safety monograph for MYCELEX (MYCELEX). | Azole Antifungal | caution |
MYCELEX-7 Comprehensive clinical and safety monograph for MYCELEX-7 (MYCELEX-7). | Azole Antifungal | caution |
MYCELEX-7 COMBINATION PACK Comprehensive clinical and safety monograph for MYCELEX-7 COMBINATION PACK (MYCELEX-7 COMBINATION PACK). | Antifungal | caution |
MYCELEX-G Comprehensive clinical and safety monograph for MYCELEX-G (MYCELEX-G). | Antifungal | caution |
MYCO-TRIACET II Comprehensive clinical and safety monograph for MYCO-TRIACET II (MYCO-TRIACET II). | Antifungal Corticosteroid Combination | caution |
MYCOLOG-II Comprehensive clinical and safety monograph for MYCOLOG-II (MYCOLOG-II). | Antifungal Corticosteroid Combination | caution |
MYCOSTATIN Comprehensive clinical and safety monograph for MYCOSTATIN (MYCOSTATIN). | Antifungal | caution |
MYHIBBIN Comprehensive clinical and safety monograph for MYHIBBIN (MYHIBBIN). | Antifungal | caution |
MYIDYL Comprehensive clinical and safety monograph for MYIDYL (MYIDYL). | Antifungal | caution |
NAFTIFINE HYDROCHLORIDE Comprehensive clinical and safety monograph for NAFTIFINE HYDROCHLORIDE (NAFTIFINE HYDROCHLORIDE). | Allylamine Antifungal | caution |
NAFTIN Comprehensive clinical and safety monograph for NAFTIN (NAFTIN). | Allylamine Antifungal | caution |
NATACYN Comprehensive clinical and safety monograph for NATACYN (NATACYN). | Antifungal, Ophthalmic | caution |
NILSTAT Comprehensive clinical and safety monograph for NILSTAT (NILSTAT). | Antifungal | caution |
NIZORAL Comprehensive clinical and safety monograph for NIZORAL (NIZORAL). | Azole Antifungal | caution |
NIZORAL ANTI-DANDRUFF Comprehensive clinical and safety monograph for NIZORAL ANTI-DANDRUFF (NIZORAL ANTI-DANDRUFF). | Topical Antifungal | caution |
NOXAFIL Comprehensive clinical and safety monograph for NOXAFIL (NOXAFIL). | Antifungal | caution |
NOXAFIL POWDERMIX KIT Comprehensive clinical and safety monograph for NOXAFIL POWDERMIX KIT (NOXAFIL POWDERMIX KIT). | Antifungal | caution |
NUFYMCO Comprehensive clinical and safety monograph for NUFYMCO (NUFYMCO). | Antifungal | caution |
NYSERT Comprehensive clinical and safety monograph for NYSERT (NYSERT). | Antifungal | caution |
NYSTAFORM Comprehensive clinical and safety monograph for NYSTAFORM (NYSTAFORM). | Antifungal | caution |
NYSTATIN No significant drug interactions For topical or oral use only not for systemic use. | Antifungal | safe |
NYSTEX Comprehensive clinical and safety monograph for NYSTEX (NYSTEX). | Antifungal | caution |
NYSTOP Comprehensive clinical and safety monograph for NYSTOP (NYSTOP). | Antifungal | caution |
ORAVIG Comprehensive clinical and safety monograph for ORAVIG (ORAVIG). | Antifungal | caution |
OXICONAZOLE NITRATE Comprehensive clinical and safety monograph for OXICONAZOLE NITRATE (OXICONAZOLE NITRATE). | Topical Antifungal | caution |
OXISTAT Comprehensive clinical and safety monograph for OXISTAT (OXISTAT). | Topical Antifungal | caution |
PENLAC Comprehensive clinical and safety monograph for PENLAC (PENLAC). | Topical Antifungal | caution |
POSACONAZOLE Comprehensive clinical and safety monograph for POSACONAZOLE (POSACONAZOLE). | Azole Antifungal | caution |
POSFREA Comprehensive clinical and safety monograph for POSFREA (POSFREA). | Azole Antifungal | caution |
REZIRA Comprehensive clinical and safety monograph for REZIRA (REZIRA). | Topical Antifungal (Azole) | caution |
REZZAYO Comprehensive clinical and safety monograph for REZZAYO (REZZAYO). | Antifungal (Echinocandin) | caution |
SANSAC Comprehensive clinical and safety monograph for SANSAC (SANSAC). | Topical Antifungal | caution |
SELENIUM SULFIDE No significant drug interactions For topical use only can cause hair discoloration. | Antifungal / Antiseborrheic | safe |
SELSUN Comprehensive clinical and safety monograph for SELSUN (SELSUN). | Antifungal/Antiseborrheic | caution |
SPECTAZOLE Comprehensive clinical and safety monograph for SPECTAZOLE (SPECTAZOLE). | Antifungal | caution |
SPORANOX Comprehensive clinical and safety monograph for SPORANOX (SPORANOX). | Antifungal | caution |
TAVABOROLE Comprehensive clinical and safety monograph for TAVABOROLE (TAVABOROLE). | Antifungal (Oxaborole) | caution |
TERAZOL 3 Comprehensive clinical and safety monograph for TERAZOL 3 (TERAZOL 3). | Azole Antifungal | caution |
TERAZOL 7 Comprehensive clinical and safety monograph for TERAZOL 7 (TERAZOL 7). | Azole Antifungal | caution |
TERCONAZOLE No significant drug interactions For vaginal use only can cause vulvovaginal burning. | Antifungal | safe |
TIOCONAZOLE No significant drug interactions For topical use only not for ophthalmic use. | Antifungal | safe |
TOLAK Comprehensive clinical and safety monograph for TOLAK (TOLAK). | Antifungal | caution |
TOLSURA Comprehensive clinical and safety monograph for TOLSURA (TOLSURA). | Antifungal (Triazole) | caution |
TRIVAGIZOLE 3 Comprehensive clinical and safety monograph for TRIVAGIZOLE 3 (TRIVAGIZOLE 3). | Antibacterial/Antifungal Combination | caution |
ULTRAGRIS-165 Comprehensive clinical and safety monograph for ULTRAGRIS-165 (ULTRAGRIS-165). | Antifungal (Griseofulvin) | caution |
ULTRAGRIS-330 Comprehensive clinical and safety monograph for ULTRAGRIS-330 (ULTRAGRIS-330). | Antifungal (Griseofulvin) | caution |
VAGISTAT-1 Comprehensive clinical and safety monograph for VAGISTAT-1 (VAGISTAT-1). | Azole Antifungal | caution |
VANOBID Comprehensive clinical and safety monograph for VANOBID (VANOBID). | Antifungal and Corticosteroid Combination | caution |
VFEND Comprehensive clinical and safety monograph for VFEND (VFEND). | Antifungal | caution |
VIBISONE Comprehensive clinical and safety monograph for VIBISONE (VIBISONE). | Topical Corticosteroid with Antifungal | caution |
VITUZ Comprehensive clinical and safety monograph for VITUZ (VITUZ). | Antifungal | caution |
VORICONAZOLE Inhibits CYP3A4 increasing levels of many drugs (eg statins) Can cause visual disturbances hepatotoxicity and photosensitivity. | Azole Antifungal | avoid |
XOLEGEL Comprehensive clinical and safety monograph for XOLEGEL (XOLEGEL). | Topical Antifungal | caution |
