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Clinical Notice:OpiCalc is not a substitute for professional clinical judgment. Always verify dosages and guidelines.

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Registry Hub

Therapeutic Classification

antiviral Registry

Clinical reference for antiviral medications. Access safety monographs, dosing adjustments, and drug-drug interactions for all registered brand names and generics in this class.

Registered Medications (antiviral)

This therapeutic registry is dynamically synthesized from professional clinical sources. Listing of a medication does not imply equivalence; refer to individual monographs for head-to-head pharmacological data.

MedicationTherapeutic ClassMaternal Safety

ABREVA

Comprehensive clinical and safety monograph for ABREVA (ABREVA).

Antiviral

caution

ACYCLOVIR

Probenecid may decrease acyclovir clearance increasing its levels Maintain adequate hydration to prevent nephrotoxicity especially in elderly or dehydrated patients.

Antiviral

safe

ACYCLOVIR SODIUM

Acyclovir is considered compatible with pregnancy when clinically indicated for life-threatening maternal HSV or VZV infections. A registry of exposed pregnancies has not demonstrated an increased risk of major birth defects; however, human data are limited. Benefit outweighs risk in severe disease.

Antiviral

safe

ADEFOVIR DIPIVOXIL

Comprehensive clinical and safety monograph for ADEFOVIR DIPIVOXIL (ADEFOVIR DIPIVOXIL).

Antiviral

caution

AMANTADINE

Anticholinergic drugs may have additive side effects Use cautiously in patients with seizure history or psychiatric disorders livedo reticularis and ankle edema are common.

Antiviral / Antiparkinsonian

caution

AMANTADINE HYDROCHLORIDE

Amantadine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Animal studies have shown teratogenic and embryotoxic effects at high doses, but well-controlled human studies are lacking. Consider alternative therapies if feasible.

Antiviral / Antiparkinsonian

caution

APOGEN

Comprehensive clinical and safety monograph for APOGEN (APOGEN).

Antiviral

caution

AVACLYR

Comprehensive clinical and safety monograph for AVACLYR (AVACLYR).

Topical Antiviral

caution

BARACLUDE

Comprehensive clinical and safety monograph for BARACLUDE (BARACLUDE).

Antiviral (HBV)

caution

BILPREVDA

Comprehensive clinical and safety monograph for BILPREVDA (BILPREVDA).

Antiviral

caution

BKEMV

Comprehensive clinical and safety monograph for BKEMV (BKEMV).

Antiviral, HIV

caution

CIDOFOVIR

Probenecid is required during administration to reduce nephrotoxicity and other nephrotoxic drugs should be avoided Causes severe nephrotoxicity requires pre-hydration and renal function monitoring.

Antiviral

avoid

COPEGUS

Comprehensive clinical and safety monograph for COPEGUS (COPEGUS).

Antiviral

caution

CYTOVENE

Comprehensive clinical and safety monograph for CYTOVENE (CYTOVENE).

Antiviral Agent

caution

DENAVIR

Comprehensive clinical and safety monograph for DENAVIR (DENAVIR).

Antiviral

caution

DENDRID

Comprehensive clinical and safety monograph for DENDRID (DENDRID).

Antiviral

caution

DOCOSANOL

Comprehensive clinical and safety monograph for DOCOSANOL (DOCOSANOL).

Antiviral Agent

caution

EBANGA

Comprehensive clinical and safety monograph for EBANGA (EBANGA).

Antiviral (Ebola)

caution

EBGLYSS

Comprehensive clinical and safety monograph for EBGLYSS (EBGLYSS).

Antiviral Agent

caution

EPCLUSA

Comprehensive clinical and safety monograph for EPCLUSA (EPCLUSA).

Direct-Acting Antiviral (DAA) for Hepatitis C

caution

EPIVIR-HBV

Comprehensive clinical and safety monograph for EPIVIR-HBV (EPIVIR-HBV).

NRTI Antiviral

caution

FAMCICLOVIR

Probenecid may decrease renal excretion of penciclovir Dosage adjustment is required in renal impairment.

Antiviral

safe

FAMVIR

Comprehensive clinical and safety monograph for FAMVIR (FAMVIR).

Antiviral

caution

FAVLYXA

Comprehensive clinical and safety monograph for FAVLYXA (FAVLYXA).

Antiviral

caution

FLUMADINE

Comprehensive clinical and safety monograph for FLUMADINE (FLUMADINE).

Antiviral Agent

caution

FOSCARNET SODIUM

Nephrotoxic drugs increase risk of renal impairment Can cause renal impairment and electrolyte imbalances.

Antiviral

safe

FOSCAVIR

Comprehensive clinical and safety monograph for FOSCAVIR (FOSCAVIR).

Antiviral

caution

FUZEON

Comprehensive clinical and safety monograph for FUZEON (FUZEON).

Antiviral

caution

GANCICLOVIR

Other bone marrow suppressants may have additive effects Can cause severe myelosuppression and mutagenesis.

Antiviral

avoid

GANCICLOVIR SODIUM

Other bone marrow suppressants may have additive effects Can cause severe myelosuppression and mutagenesis.

Antiviral

avoid

GANZYK-RTU

Comprehensive clinical and safety monograph for GANZYK-RTU (GANZYK-RTU).

Antiviral (CMV)

caution

HARVONI

Comprehensive clinical and safety monograph for HARVONI (HARVONI).

Antiviral

caution

HEPSERA

Comprehensive clinical and safety monograph for HEPSERA (HEPSERA).

Antiviral

caution

HERNEXEOS

Comprehensive clinical and safety monograph for HERNEXEOS (HERNEXEOS).

Antiviral

caution

HERPLEX

Comprehensive clinical and safety monograph for HERPLEX (HERPLEX).

Antiviral

caution

INCIVEK

Comprehensive clinical and safety monograph for INCIVEK (INCIVEK).

Antiviral

caution

LETERMOVIR

Comprehensive clinical and safety monograph for LETERMOVIR (LETERMOVIR).

Antiviral

caution

LETYBO

Comprehensive clinical and safety monograph for LETYBO (LETYBO).

Antiviral

caution

LIVTENCITY

Comprehensive clinical and safety monograph for LIVTENCITY (LIVTENCITY).

Antiviral

caution

MAVYRET

Comprehensive clinical and safety monograph for MAVYRET (MAVYRET).

Antiviral Agent

caution

NORVIR

Comprehensive clinical and safety monograph for NORVIR (NORVIR).

Protease Inhibitor (Antiviral)

caution

PAXLOVID (COPACKAGED)

Comprehensive clinical and safety monograph for PAXLOVID (COPACKAGED) (PAXLOVID (COPACKAGED)).

Antiviral Protease Inhibitor

caution

PENCICLOVIR

No significant drug interactions For topical use only not for ophthalmic or oral use.

Antiviral

safe

PHEXXI

Comprehensive clinical and safety monograph for PHEXXI (PHEXXI).

Topical Antiviral

caution

PREVYMIS

Comprehensive clinical and safety monograph for PREVYMIS (PREVYMIS).

Antiviral (CMV)

caution

PREZCOBIX

Comprehensive clinical and safety monograph for PREZCOBIX (PREZCOBIX).

HIV Antiviral (Protease Inhibitor Combination)

caution

PREZCOBIX PED

Comprehensive clinical and safety monograph for PREZCOBIX PED (PREZCOBIX PED).

HIV Antiviral (Protease Inhibitor Combination)

caution

PREZISTA

Comprehensive clinical and safety monograph for PREZISTA (PREZISTA).

HIV Antiviral (Protease Inhibitor)

caution

REBETOL

Comprehensive clinical and safety monograph for REBETOL (REBETOL).

Antiviral

caution

RELENZA

Comprehensive clinical and safety monograph for RELENZA (RELENZA).

Neuraminidase Inhibitor Antiviral

caution

REZENOPY

Comprehensive clinical and safety monograph for REZENOPY (REZENOPY).

Antiviral (Nucleoside Analog)

caution

RIBASPHERE

Comprehensive clinical and safety monograph for RIBASPHERE (RIBASPHERE).

Antiviral (Nucleoside Analog)

caution

RIMANTADINE HYDROCHLORIDE

Acetaminophen and aspirin may decrease rimantadine levels Can cause CNS side effects like insomnia and dizziness.

Antiviral

safe

SOVALDI

Comprehensive clinical and safety monograph for SOVALDI (SOVALDI).

Direct-acting antiviral

caution

STOXIL

Comprehensive clinical and safety monograph for STOXIL (STOXIL).

Ophthalmic Antiviral

caution

SYLATRON

Comprehensive clinical and safety monograph for SYLATRON (SYLATRON).

Interferon Antineoplastic/Antiviral

caution

SYMADINE

Comprehensive clinical and safety monograph for SYMADINE (SYMADINE).

Antiviral and Antiparkinsonian

caution

SYMMETREL

Comprehensive clinical and safety monograph for SYMMETREL (SYMMETREL).

Antiviral and Antiparkinsonian

caution

TECHNIVIE

Comprehensive clinical and safety monograph for TECHNIVIE (TECHNIVIE).

Direct-acting antiviral

caution

TPOXX

Comprehensive clinical and safety monograph for TPOXX (TPOXX).

Antiviral Agent

caution

TRIFLURIDINE

Comprehensive clinical and safety monograph for TRIFLURIDINE (TRIFLURIDINE).

Antiviral

caution

TYZEKA

Comprehensive clinical and safety monograph for TYZEKA (TYZEKA).

Antiviral, Hepatitis B

caution

VALACYCLOVIR HYDROCHLORIDE

Probenecid may decrease acyclovir clearance increasing its levels Maintain adequate hydration to prevent nephrotoxicity especially in elderly or dehydrated patients.

Antiviral

safe

VALCYTE

Comprehensive clinical and safety monograph for VALCYTE (VALCYTE).

Antiviral Agent

caution

VALGANCICLOVIR HYDROCHLORIDE

Probenecid may decrease ganciclovir excretion Can cause severe myelosuppression and mutagenesis.

Antiviral

avoid

VALTREX

Comprehensive clinical and safety monograph for VALTREX (VALTREX).

Nucleoside Analog Antiviral

caution

VANRAFIA

Comprehensive clinical and safety monograph for VANRAFIA (VANRAFIA).

Adamantane Antiviral

caution

VEKLURY

Comprehensive clinical and safety monograph for VEKLURY (VEKLURY).

Antiviral

caution

VEREGEN

Comprehensive clinical and safety monograph for VEREGEN (VEREGEN).

Topical Antiviral

caution

VIEKIRA PAK (COPACKAGED)

Comprehensive clinical and safety monograph for VIEKIRA PAK (COPACKAGED) (VIEKIRA PAK (COPACKAGED)).

Hepatitis C Antiviral Combination

caution

VIEKIRA XR

Comprehensive clinical and safety monograph for VIEKIRA XR (VIEKIRA XR).

Hepatitis C Antiviral Combination

caution

VIRA-A

Comprehensive clinical and safety monograph for VIRA-A (VIRA-A).

Antiviral (Nucleoside Analog)

caution

VIRAZOLE

Comprehensive clinical and safety monograph for VIRAZOLE (VIRAZOLE).

Antiviral (Nucleoside Analog)

caution

VIROPTIC

Comprehensive clinical and safety monograph for VIROPTIC (VIROPTIC).

Antiviral (Ophthalmic)

caution

VISTIDE

Comprehensive clinical and safety monograph for VISTIDE (VISTIDE).

Antiviral

caution

VITRASERT

Comprehensive clinical and safety monograph for VITRASERT (VITRASERT).

Antiviral

caution

VITRAVENE PRESERVATIVE FREE

Comprehensive clinical and safety monograph for VITRAVENE PRESERVATIVE FREE (VITRAVENE PRESERVATIVE FREE).

Antiviral

caution

VOSEVI

Comprehensive clinical and safety monograph for VOSEVI (VOSEVI).

Direct-Acting Antiviral Combination

caution

XERESE

Comprehensive clinical and safety monograph for XERESE (XERESE).

Antiviral

caution

XOFLUZA

Comprehensive clinical and safety monograph for XOFLUZA (XOFLUZA).

Antiviral

caution

ZEPATIER

Comprehensive clinical and safety monograph for ZEPATIER (ZEPATIER).

Direct-Acting Antiviral (HCV)

caution

ZIRGAN

Comprehensive clinical and safety monograph for ZIRGAN (ZIRGAN).

Antiviral

caution

ZOVIRAX

Comprehensive clinical and safety monograph for ZOVIRAX (ZOVIRAX).

Antiviral

caution