ACETAZOLAMIDE Comprehensive clinical and safety monograph for ACETAZOLAMIDE (ACETAZOLAMIDE). | Carbonic Anhydrase Inhibitor | caution |
ACETAZOLAMIDE SODIUM Comprehensive clinical and safety monograph for ACETAZOLAMIDE SODIUM (ACETAZOLAMIDE SODIUM). | Carbonic Anhydrase Inhibitor | caution |
ALLZITAL Comprehensive clinical and safety monograph for ALLZITAL (ALLZITAL). | Barbiturate Analgesic Combination | caution |
AMLODIPINE AND OLMESARTAN MEDOXOMIL NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
AMLODIPINE BESYLATE AND VALSARTAN NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
AMLODIPINE BESYLATE, VALSARTAN AND HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
AVALIDE Comprehensive clinical and safety monograph for AVALIDE (AVALIDE). | ARB and Thiazide Diuretic Combination | caution |
AVAPRO Comprehensive clinical and safety monograph for AVAPRO (AVAPRO). | Antihypertensive (ARB) | caution |
AXOTAL Comprehensive clinical and safety monograph for AXOTAL (AXOTAL). | Barbiturate Combination Analgesic | caution |
AZOPT Comprehensive clinical and safety monograph for AZOPT (AZOPT). | Carbonic Anhydrase Inhibitor | caution |
BENICAR HCT Comprehensive clinical and safety monograph for BENICAR HCT (BENICAR HCT). | ARB + Thiazide Diuretic | caution |
BREVITAL SODIUM Comprehensive clinical and safety monograph for BREVITAL SODIUM (BREVITAL SODIUM). | Barbiturate Anesthetic | caution |
BRINZOLAMIDE Oral carbonic anhydrase inhibitors may have additive effects Salicylates may cause acid-base disturbances Sulfonamide hypersensitivity reactions may occur. | Carbonic Anhydrase Inhibitor | safe |
BUCET Comprehensive clinical and safety monograph for BUCET (BUCET). | Barbiturate Combination Analgesic | caution |
BUTABARB Comprehensive clinical and safety monograph for BUTABARB (BUTABARB). | Barbiturate | caution |
BUTABARBITAL Comprehensive clinical and safety monograph for BUTABARBITAL (BUTABARBITAL). | Barbiturate | caution |
BUTABARBITAL SODIUM Comprehensive clinical and safety monograph for BUTABARBITAL SODIUM (BUTABARBITAL SODIUM). | Barbiturate | caution |
BUTALAN Comprehensive clinical and safety monograph for BUTALAN (BUTALAN). | Barbiturate | caution |
BUTALBITAL AND ACETAMINOPHEN Comprehensive clinical and safety monograph for BUTALBITAL AND ACETAMINOPHEN (BUTALBITAL AND ACETAMINOPHEN). | Barbiturate Combination | caution |
BUTALBITAL, ACETAMINOPHEN AND CAFFEINE Comprehensive clinical and safety monograph for BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (BUTALBITAL, ACETAMINOPHEN AND CAFFEINE). | Barbiturate Combination | caution |
BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE CNS depressants including alcohol and benzodiazepines increase sedation risk Life-threatening respiratory depression may occur especially in CYP2D6 ultra-rapid metabolizers. | Barbiturate + Analgesic | avoid |
BUTAPAP Comprehensive clinical and safety monograph for BUTAPAP (BUTAPAP). | Barbiturate Combination | caution |
BUTICAPS Comprehensive clinical and safety monograph for BUTICAPS (BUTICAPS). | Barbiturate | caution |
BUTISOL SODIUM Comprehensive clinical and safety monograph for BUTISOL SODIUM (BUTISOL SODIUM). | Barbiturate | caution |
CANDESARTAN CILEXETIL NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
CARBIDOPA Nonselective MAOIs are contraindicated When given without levodopa it has no therapeutic effect. | Decarboxylase Inhibitor | safe |
DARANIDE Comprehensive clinical and safety monograph for DARANIDE (DARANIDE). | Carbonic Anhydrase Inhibitor | caution |
DIAMOX Comprehensive clinical and safety monograph for DIAMOX (DIAMOX). | Carbonic Anhydrase Inhibitor | caution |
DICHLORPHENAMIDE Comprehensive clinical and safety monograph for DICHLORPHENAMIDE (DICHLORPHENAMIDE). | Carbonic Anhydrase Inhibitor | caution |
DIOVAN Comprehensive clinical and safety monograph for DIOVAN (DIOVAN). | ARB Antihypertensive | caution |
DORIBAX Comprehensive clinical and safety monograph for DORIBAX (DORIBAX). | Carbapenem Antibiotic | caution |
DORZOLAMIDE HYDROCHLORIDE Comprehensive clinical and safety monograph for DORZOLAMIDE HYDROCHLORIDE (DORZOLAMIDE HYDROCHLORIDE). | Carbonic Anhydrase Inhibitor | caution |
DUOPA Comprehensive clinical and safety monograph for DUOPA (DUOPA). | Decarboxylase Inhibitor/Dopamine Precursor Combination | caution |
EPROSARTAN MESYLATE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
ERTAPENEM SODIUM Valproic acid levels may be significantly reduced Can cause seizures and hypersensitivity reactions. | Carbapenem Antibiotic | safe |
ESGIC Comprehensive clinical and safety monograph for ESGIC (ESGIC). | Barbiturate Combination | caution |
ESGIC-PLUS Comprehensive clinical and safety monograph for ESGIC-PLUS (ESGIC-PLUS). | Barbiturate/Narcotic Combination | caution |
ETHAMIDE Comprehensive clinical and safety monograph for ETHAMIDE (ETHAMIDE). | Carbonic Anhydrase Inhibitor | caution |
FILSPARI Comprehensive clinical and safety monograph for FILSPARI (FILSPARI). | Endothelin Receptor Antagonist / ARB | caution |
FIORINAL Comprehensive clinical and safety monograph for FIORINAL (FIORINAL). | Barbiturate Analgesic Combination | caution |
HYDROCHLOROTHIAZIDE; IRBESARTAN NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
HYDROCHLOROTHIAZIDE; VALSARTAN NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
IMIPENEM AND CILASTATIN Comprehensive clinical and safety monograph for IMIPENEM AND CILASTATIN (IMIPENEM AND CILASTATIN). | Carbapenem Antibiotic Combination | caution |
INVANZ Comprehensive clinical and safety monograph for INVANZ (INVANZ). | Carbapenem Antibiotic | caution |
IRBESARTAN NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
IRBESARTAN AND HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
IRBESARTAN HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
KEVEYIS Comprehensive clinical and safety monograph for KEVEYIS (KEVEYIS). | Carbonic Anhydrase Inhibitor | caution |
LODOSYN Comprehensive clinical and safety monograph for LODOSYN (LODOSYN). | Decarboxylase Inhibitor | caution |
Losartan Contraindicated throughout pregnancy. ARBs carry the same fetopathic mechanism as ACE inhibitors: inhibition of the renin-angiotensin system (RAS) disrupts fetal renal development. Second and third trimester exposure causes fetal renal tubular dysgenesis, oligohydramnios, skull hypoplasia, limb contractures, and fetal/neonatal death. First-trimester risk for cardiac defects has been reported. Discontinue immediately upon confirmed pregnancy. | ARB | avoid |
LOSARTAN POTASSIUM NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
MEROPENEM Valproic acid levels may be significantly reduced Can cause seizures and hypersensitivity reactions. | Carbapenem Antibiotic | safe |
MERREM IV Comprehensive clinical and safety monograph for MERREM IV (MERREM IV). | Carbapenem Antibiotic | caution |
METHAZOLAMIDE Comprehensive clinical and safety monograph for METHAZOLAMIDE (METHAZOLAMIDE). | Carbonic Anhydrase Inhibitor | caution |
METHOHEXITAL SODIUM Comprehensive clinical and safety monograph for METHOHEXITAL SODIUM (METHOHEXITAL SODIUM). | Barbiturate Anesthetic | caution |
MICARDIS HCT Comprehensive clinical and safety monograph for MICARDIS HCT (MICARDIS HCT). | Antihypertensive Combination (ARB + Thiazide Diuretic) | caution |
MICRAININ Comprehensive clinical and safety monograph for MICRAININ (MICRAININ). | Barbiturate Combination Analgesic | caution |
NEMBUTAL Comprehensive clinical and safety monograph for NEMBUTAL (NEMBUTAL). | Barbiturate | caution |
NEMBUTAL SODIUM Comprehensive clinical and safety monograph for NEMBUTAL SODIUM (NEMBUTAL SODIUM). | Barbiturate | caution |
NEPTAZANE Comprehensive clinical and safety monograph for NEPTAZANE (NEPTAZANE). | Carbonic Anhydrase Inhibitor | caution |
OLMESARTAN MEDOXOMIL NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
OLMESARTAN MEDOXOMIL AND HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
OLMESARTAN MEDOXOMIL, AMLODIPINE AND HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
ORNIDYL Comprehensive clinical and safety monograph for ORNIDYL (ORNIDYL). | Ornithine decarboxylase inhibitor | caution |
PENTOBARBITAL SODIUM CNS depressants may enhance sedative effects Can cause respiratory depression and dependence. | Barbiturate | avoid |
PENTOTHAL Comprehensive clinical and safety monograph for PENTOTHAL (PENTOTHAL). | Barbiturate Anesthetic | caution |
PHRENILIN Comprehensive clinical and safety monograph for PHRENILIN (PHRENILIN). | Barbiturate/Analgesic Combination | caution |
PHRENILIN FORTE Comprehensive clinical and safety monograph for PHRENILIN FORTE (PHRENILIN FORTE). | Barbiturate Combination Analgesic | caution |
PRIMAXIN Comprehensive clinical and safety monograph for PRIMAXIN (PRIMAXIN). | Carbapenem Antibiotic | caution |
RECARBRIO Comprehensive clinical and safety monograph for RECARBRIO (RECARBRIO). | Antibiotic (Carbapenem) | caution |
RYTARY Comprehensive clinical and safety monograph for RYTARY (RYTARY). | Decarboxylase Inhibitor/Dopamine Precursor | caution |
SACUBITRIL AND VALSARTAN NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
SECOBARBITAL SODIUM CNS depressants may enhance sedative effects Can cause respiratory depression and dependence. | Barbiturate | avoid |
SECONAL SODIUM Comprehensive clinical and safety monograph for SECONAL SODIUM (SECONAL SODIUM). | Barbiturate Sedative-Hypnotic | caution |
SEDAPAP Comprehensive clinical and safety monograph for SEDAPAP (SEDAPAP). | Barbiturate Combination Analgesic | caution |
SODIUM BUTABARBITAL Comprehensive clinical and safety monograph for SODIUM BUTABARBITAL (SODIUM BUTABARBITAL). | Barbiturate | caution |
SODIUM PENTOBARBITAL CNS depressants may enhance sedative effects Can cause respiratory depression and dependence. | Barbiturate | avoid |
SURITAL Comprehensive clinical and safety monograph for SURITAL (SURITAL). | Barbiturate Anesthetic | caution |
TELMISARTAN NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
TELMISARTAN AND AMLODIPINE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
TELMISARTAN AND HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
TELMISARTAN; HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
TENCON Comprehensive clinical and safety monograph for TENCON (TENCON). | Barbiturate combination analgesic | caution |
TEVETEN HCT Comprehensive clinical and safety monograph for TEVETEN HCT (TEVETEN HCT). | ARB + Thiazide Diuretic Combination | caution |
TRAVERT 10% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for TRAVERT 10% IN PLASTIC CONTAINER (TRAVERT 10% IN PLASTIC CONTAINER). | Carbohydrate Solution | caution |
TREZIX Comprehensive clinical and safety monograph for TREZIX (TREZIX). | Barbiturate Combination Analgesic | caution |
TRUSOPT Comprehensive clinical and safety monograph for TRUSOPT (TRUSOPT). | Carbonic Anhydrase Inhibitor | caution |
VABOMERE Comprehensive clinical and safety monograph for VABOMERE (VABOMERE). | Carbapenem Antibiotic | caution |
VALSARTAN NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
VALSARTAN AND HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
VALSARTAN; HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus. | ARB | avoid |
VANIQA Comprehensive clinical and safety monograph for VANIQA (VANIQA). | Ornithine Decarboxylase Inhibitor | caution |
VTAMA Comprehensive clinical and safety monograph for VTAMA (VTAMA). | Aryl Hydrocarbon Receptor Agonist | caution |
XBRYK Comprehensive clinical and safety monograph for XBRYK (XBRYK). | Barbiturate Analgesic Combination | caution |
