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Registry Hub

Therapeutic Classification

local anesthetic Registry

Clinical reference for local anesthetic medications. Access safety monographs, dosing adjustments, and drug-drug interactions for all registered brand names and generics in this class.

Registered Medications (local anesthetic)

This therapeutic registry is dynamically synthesized from professional clinical sources. Listing of a medication does not imply equivalence; refer to individual monographs for head-to-head pharmacological data.

MedicationTherapeutic ClassMaternal Safety

ALCAINE

Comprehensive clinical and safety monograph for ALCAINE (ALCAINE).

Local Anesthetic

caution

ALPHACAINE

Comprehensive clinical and safety monograph for ALPHACAINE (ALPHACAINE).

Local Anesthetic

caution

ALPHACAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for ALPHACAINE HYDROCHLORIDE (ALPHACAINE HYDROCHLORIDE).

Local Anesthetic

caution

ANOQUAN

Comprehensive clinical and safety monograph for ANOQUAN (ANOQUAN).

Local Anesthetic

caution

ARESTOCAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for ARESTOCAINE HYDROCHLORIDE (ARESTOCAINE HYDROCHLORIDE).

Local Anesthetic

caution

ARESTOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN

Comprehensive clinical and safety monograph for ARESTOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN (ARESTOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN).

Local Anesthetic with Vasoconstrictor

caution

BUPIVACAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for BUPIVACAINE HYDROCHLORIDE (BUPIVACAINE HYDROCHLORIDE).

Local Anesthetic

caution

BUPIVACAINE HYDROCHLORIDE KIT

Comprehensive clinical and safety monograph for BUPIVACAINE HYDROCHLORIDE KIT (BUPIVACAINE HYDROCHLORIDE KIT).

Local Anesthetic

caution

BUPIVACAINE HYDROCHLORIDE PRESERVATIVE FREE

Comprehensive clinical and safety monograph for BUPIVACAINE HYDROCHLORIDE PRESERVATIVE FREE (BUPIVACAINE HYDROCHLORIDE PRESERVATIVE FREE).

Local Anesthetic

caution

BUPIVACAINE LIPOSOME

Comprehensive clinical and safety monograph for BUPIVACAINE LIPOSOME (BUPIVACAINE LIPOSOME).

Local Anesthetic

caution

CARBOCAINE

Comprehensive clinical and safety monograph for CARBOCAINE (CARBOCAINE).

Local Anesthetic

caution

CARBOCAINE W/ NEO-COBEFRIN

Comprehensive clinical and safety monograph for CARBOCAINE W/ NEO-COBEFRIN (CARBOCAINE W/ NEO-COBEFRIN).

Local Anesthetic Combination

caution

CHIROCAINE

Comprehensive clinical and safety monograph for CHIROCAINE (CHIROCAINE).

Local Anesthetic

caution

CHLOROPROCAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for CHLOROPROCAINE HYDROCHLORIDE (CHLOROPROCAINE HYDROCHLORIDE).

Local Anesthetic

caution

CITANEST

Comprehensive clinical and safety monograph for CITANEST (CITANEST).

Local Anesthetic (Amide)

caution

CITANEST FORTE

Comprehensive clinical and safety monograph for CITANEST FORTE (CITANEST FORTE).

Local Anesthetic (Amide) with Vasoconstrictor

caution

CITANEST FORTE DENTAL

Comprehensive clinical and safety monograph for CITANEST FORTE DENTAL (CITANEST FORTE DENTAL).

Local Anesthetic (Dental)

caution

CITANEST PLAIN

Comprehensive clinical and safety monograph for CITANEST PLAIN (CITANEST PLAIN).

Local Anesthetic (Amide)

caution

CITANEST PLAIN DENTAL

Comprehensive clinical and safety monograph for CITANEST PLAIN DENTAL (CITANEST PLAIN DENTAL).

Local Anesthetic (Dental)

caution

CYCLAINE

Comprehensive clinical and safety monograph for CYCLAINE (CYCLAINE).

Local Anesthetic

caution

DECADRON W/ XYLOCAINE

Comprehensive clinical and safety monograph for DECADRON W/ XYLOCAINE (DECADRON W/ XYLOCAINE).

Corticosteroid/Local Anesthetic Combination

caution

DENTIPATCH

Comprehensive clinical and safety monograph for DENTIPATCH (DENTIPATCH).

Local Anesthetic

caution

DURANEST

Comprehensive clinical and safety monograph for DURANEST (DURANEST).

Local Anesthetic

caution

EMLA

Comprehensive clinical and safety monograph for EMLA (EMLA).

Local Anesthetic

caution

EXPAREL

Comprehensive clinical and safety monograph for EXPAREL (EXPAREL).

Local Anesthetic

caution

GLYDO

Comprehensive clinical and safety monograph for GLYDO (GLYDO).

Local Anesthetic (Amide)

caution

HEAVY SOLUTION NUPERCAINE

Comprehensive clinical and safety monograph for HEAVY SOLUTION NUPERCAINE (HEAVY SOLUTION NUPERCAINE).

Local Anesthetic

caution

IONTOCAINE

Comprehensive clinical and safety monograph for IONTOCAINE (IONTOCAINE).

Local Anesthetic

caution

ISOCAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for ISOCAINE HYDROCHLORIDE (ISOCAINE HYDROCHLORIDE).

Local Anesthetic

caution

ISOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN

Comprehensive clinical and safety monograph for ISOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN (ISOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN).

Local Anesthetic with Vasoconstrictor

caution

LARYNG-O-JET KIT

Comprehensive clinical and safety monograph for LARYNG-O-JET KIT (LARYNG-O-JET KIT).

Local Anesthetic

caution

LARYNGOTRACHEAL ANESTHESIA KIT

Comprehensive clinical and safety monograph for LARYNGOTRACHEAL ANESTHESIA KIT (LARYNGOTRACHEAL ANESTHESIA KIT).

Local Anesthetic

caution

LICART

Comprehensive clinical and safety monograph for LICART (LICART).

Local Anesthetic

caution

LIDOCAINE

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE AND PRILOCAINE

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 0.1% AND DEXTROSE 5% IN PLASTIC CONTAINER

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 0.2% AND DEXTROSE 5% IN PLASTIC CONTAINER

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 0.2% IN DEXTROSE 5%

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 0.2% IN DEXTROSE 5% IN PLASTIC CONTAINER

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 0.4% AND DEXTROSE 5% IN PLASTIC CONTAINER

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 0.4% IN DEXTROSE 5%

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 0.4% IN DEXTROSE 5% IN PLASTIC CONTAINER

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 0.8% AND DEXTROSE 5% IN PLASTIC CONTAINER

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 0.8% IN DEXTROSE 5% IN PLASTIC CONTAINER

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE 5% AND DEXTROSE 7.5%

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE IN PLASTIC CONTAINER

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE PRESERVATIVE FREE

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE PRESERVATIVE FREE IN PLASTIC CONTAINER

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE VISCOUS

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCAINE VISCOUS

Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.

Local Anesthetic / Antiarrhythmic (Class Ib)

safe

LIDOCATON

Comprehensive clinical and safety monograph for LIDOCATON (LIDOCATON).

Local Anesthetic

caution

LIDODERM

Comprehensive clinical and safety monograph for LIDODERM (LIDODERM).

Local Anesthetic

caution

LIDOPEN

Comprehensive clinical and safety monograph for LIDOPEN (LIDOPEN).

Local Anesthetic

caution

LIDOSITE TOPICAL SYSTEM KIT

Comprehensive clinical and safety monograph for LIDOSITE TOPICAL SYSTEM KIT (LIDOSITE TOPICAL SYSTEM KIT).

Local Anesthetic

caution

LIGNOSPAN FORTE

Comprehensive clinical and safety monograph for LIGNOSPAN FORTE (LIGNOSPAN FORTE).

Local Anesthetic with Vasoconstrictor

caution

LIGNOSPAN STANDARD

Comprehensive clinical and safety monograph for LIGNOSPAN STANDARD (LIGNOSPAN STANDARD).

Local Anesthetic with Vasoconstrictor

caution

MARCAINE

Comprehensive clinical and safety monograph for MARCAINE (MARCAINE).

Local Anesthetic

caution

MARCAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for MARCAINE HYDROCHLORIDE (MARCAINE HYDROCHLORIDE).

Local Anesthetic

caution

MARCAINE HYDROCHLORIDE PRESERVATIVE FREE

Comprehensive clinical and safety monograph for MARCAINE HYDROCHLORIDE PRESERVATIVE FREE (MARCAINE HYDROCHLORIDE PRESERVATIVE FREE).

Local Anesthetic

caution

MEPIVACAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for MEPIVACAINE HYDROCHLORIDE (MEPIVACAINE HYDROCHLORIDE).

Local Anesthetic

caution

MEPIVACAINE HYDROCHLORIDE W/ LEVONORDEFRIN

Comprehensive clinical and safety monograph for MEPIVACAINE HYDROCHLORIDE W/ LEVONORDEFRIN (MEPIVACAINE HYDROCHLORIDE W/ LEVONORDEFRIN).

Local Anesthetic with Vasoconstrictor

caution

NAROPIN

Comprehensive clinical and safety monograph for NAROPIN (NAROPIN).

Local Anesthetic

caution

NESACAINE

Comprehensive clinical and safety monograph for NESACAINE (NESACAINE).

Local Anesthetic

caution

NESACAINE-MPF

Comprehensive clinical and safety monograph for NESACAINE-MPF (NESACAINE-MPF).

Local Anesthetic

caution

NOVOCAIN

Comprehensive clinical and safety monograph for NOVOCAIN (NOVOCAIN).

Local Anesthetic

caution

OCTOCAINE

Comprehensive clinical and safety monograph for OCTOCAINE (OCTOCAINE).

Local anesthetic

caution

ORABLOC

Comprehensive clinical and safety monograph for ORABLOC (ORABLOC).

Local Anesthetic (Dental)

caution

PARACAINE

Comprehensive clinical and safety monograph for PARACAINE (PARACAINE).

Local Anesthetic

caution

PEDIATRIC LTA KIT

Comprehensive clinical and safety monograph for PEDIATRIC LTA KIT (PEDIATRIC LTA KIT).

Local Anesthetic

caution

POLOCAINE

Comprehensive clinical and safety monograph for POLOCAINE (POLOCAINE).

Local Anesthetic

caution

POLOCAINE W/ LEVONORDEFRIN

Comprehensive clinical and safety monograph for POLOCAINE W/ LEVONORDEFRIN (POLOCAINE W/ LEVONORDEFRIN).

Local Anesthetic Combination

caution

POLOCAINE-MPF

Comprehensive clinical and safety monograph for POLOCAINE-MPF (POLOCAINE-MPF).

Local Anesthetic

caution

POSIMIR

Comprehensive clinical and safety monograph for POSIMIR (POSIMIR).

Local Anesthetic

caution

PRILOCAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for PRILOCAINE HYDROCHLORIDE (PRILOCAINE HYDROCHLORIDE).

Local Anesthetic

caution

PROCAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for PROCAINE HYDROCHLORIDE (PROCAINE HYDROCHLORIDE).

Local Anesthetic

caution

RAVOCAINE AND NOVOCAIN W/ LEVOPHED

Comprehensive clinical and safety monograph for RAVOCAINE AND NOVOCAIN W/ LEVOPHED (RAVOCAINE AND NOVOCAIN W/ LEVOPHED).

Local Anesthetic Combination

caution

RAVOCAINE AND NOVOCAIN W/ NEO-COBEFRIN

Comprehensive clinical and safety monograph for RAVOCAINE AND NOVOCAIN W/ NEO-COBEFRIN (RAVOCAINE AND NOVOCAIN W/ NEO-COBEFRIN).

Local Anesthetic Combination

caution

ROMVIMZA

Comprehensive clinical and safety monograph for ROMVIMZA (ROMVIMZA).

Local Anesthetic

caution

ROPIVACAINE HYDROCHLORIDE

Other local anesthetics or drugs that cause methemoglobinemia can have additive effects Can cause CNS toxicity and methemoglobinemia.

Local Anesthetic

safe

SCANDONEST L

Comprehensive clinical and safety monograph for SCANDONEST L (SCANDONEST L).

Local Anesthetic

caution

SCANDONEST PLAIN

Comprehensive clinical and safety monograph for SCANDONEST PLAIN (SCANDONEST PLAIN).

Local Anesthetic

caution

SENSORCAINE

Comprehensive clinical and safety monograph for SENSORCAINE (SENSORCAINE).

Local Anesthetic

caution

SEPTOCAINE

Comprehensive clinical and safety monograph for SEPTOCAINE (SEPTOCAINE).

Local Anesthetic

caution

SYNERA

Comprehensive clinical and safety monograph for SYNERA (SYNERA).

Local Anesthetic

caution

TETRACAINE HYDROCHLORIDE

Comprehensive clinical and safety monograph for TETRACAINE HYDROCHLORIDE (TETRACAINE HYDROCHLORIDE).

Local Anesthetic

caution

VIVACAINE

Comprehensive clinical and safety monograph for VIVACAINE (VIVACAINE).

Local Anesthetic

caution

XARACOLL

Comprehensive clinical and safety monograph for XARACOLL (XARACOLL).

Local Anesthetic

caution

XYLOCAINE

Comprehensive clinical and safety monograph for XYLOCAINE (XYLOCAINE).

Local Anesthetic

caution

XYLOCAINE 1.5% W/ DEXTROSE 7.5%

Comprehensive clinical and safety monograph for XYLOCAINE 1.5% W/ DEXTROSE 7.5% (XYLOCAINE 1.5% W/ DEXTROSE 7.5%).

Local Anesthetic

caution

XYLOCAINE 4% PRESERVATIVE FREE

Comprehensive clinical and safety monograph for XYLOCAINE 4% PRESERVATIVE FREE (XYLOCAINE 4% PRESERVATIVE FREE).

Local Anesthetic

caution

XYLOCAINE 5% W/ GLUCOSE 7.5%

Comprehensive clinical and safety monograph for XYLOCAINE 5% W/ GLUCOSE 7.5% (XYLOCAINE 5% W/ GLUCOSE 7.5%).

Local Anesthetic

caution

XYLOCAINE DENTAL

Comprehensive clinical and safety monograph for XYLOCAINE DENTAL (XYLOCAINE DENTAL).

Local Anesthetic

caution

XYLOCAINE PRESERVATIVE FREE

Comprehensive clinical and safety monograph for XYLOCAINE PRESERVATIVE FREE (XYLOCAINE PRESERVATIVE FREE).

Local Anesthetic

caution

XYLOCAINE VISCOUS

Comprehensive clinical and safety monograph for XYLOCAINE VISCOUS (XYLOCAINE VISCOUS).

Local Anesthetic

caution

ZYNRELEF KIT

Comprehensive clinical and safety monograph for ZYNRELEF KIT (ZYNRELEF KIT).

Local Anesthetic and NSAID Combination

caution