Therapeutic Classification

local anesthetic Registry

Clinical reference for local anesthetic medications. Access safety monographs, dosing adjustments, and drug-drug interactions for all registered brand names and generics in this class.

Registered Medications (local anesthetic)

Medication	Therapeutic Class	Maternal Safety
LIDOCAINE Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE AND PRILOCAINE Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 0.1% AND DEXTROSE 5% IN PLASTIC CONTAINER Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 0.2% AND DEXTROSE 5% IN PLASTIC CONTAINER Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 0.2% IN DEXTROSE 5% Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 0.2% IN DEXTROSE 5% IN PLASTIC CONTAINER Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 0.4% AND DEXTROSE 5% IN PLASTIC CONTAINER Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 0.4% IN DEXTROSE 5% Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 0.4% IN DEXTROSE 5% IN PLASTIC CONTAINER Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 0.8% AND DEXTROSE 5% IN PLASTIC CONTAINER Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 0.8% IN DEXTROSE 5% IN PLASTIC CONTAINER Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE 5% AND DEXTROSE 7.5% Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE IN PLASTIC CONTAINER Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE PRESERVATIVE FREE Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE PRESERVATIVE FREE IN PLASTIC CONTAINER Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE VISCOUS Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
LIDOCAINE VISCOUS Beta-blockers may increase the risk of lidocaine toxicity Can cause CNS toxicity (seizures) and cardiovascular collapse.	Local Anesthetic / Antiarrhythmic (Class Ib)	safe
ROPIVACAINE HYDROCHLORIDE Other local anesthetics or drugs that cause methemoglobinemia can have additive effects Can cause CNS toxicity and methemoglobinemia.	Local Anesthetic	safe

This therapeutic registry is dynamically synthesized from professional clinical sources. Listing of a medication does not imply equivalence; refer to individual monographs for head-to-head pharmacological data.