Therapeutic Classification

modulator Registry

Clinical reference for modulator medications. Access safety monographs, dosing adjustments, and drug-drug interactions for all registered brand names and generics in this class.

Registered Medications (modulator)

Medication	Therapeutic Class	Maternal Safety
ADDYI Comprehensive clinical and safety monograph for ADDYI (ADDYI).	Serotonin Receptor Agonist/Modulator	caution
ALFERON N INJECTION Comprehensive clinical and safety monograph for ALFERON N INJECTION (ALFERON N INJECTION).	Interferon Immunomodulator	caution
ALYMSYS Comprehensive clinical and safety monograph for ALYMSYS (ALYMSYS).	Immunomodulator	caution
ANKTIVA Comprehensive clinical and safety monograph for ANKTIVA (ANKTIVA).	Immunomodulator	caution
AVONEX Comprehensive clinical and safety monograph for AVONEX (AVONEX).	Immunomodulator (Interferon)	caution
CLOMID Comprehensive clinical and safety monograph for CLOMID (CLOMID).	Selective Estrogen Receptor Modulator	caution
CLOMIPHENE CITRATE No significant drug interactions May cause visual disturbances and ovarian hyperstimulation syndrome.	Selective Estrogen Receptor Modulator (SERM)	safe
DIROXIMEL FUMARATE Comprehensive clinical and safety monograph for DIROXIMEL FUMARATE (DIROXIMEL FUMARATE).	Immunomodulator (Multiple Sclerosis)	caution
DUAVEE Comprehensive clinical and safety monograph for DUAVEE (DUAVEE).	Selective Estrogen Receptor Modulator/Estrogen Combination	caution
DUVYZAT Comprehensive clinical and safety monograph for DUVYZAT (DUVYZAT).	S1P Receptor Modulator	caution
ELUXADOLINE Comprehensive clinical and safety monograph for ELUXADOLINE (ELUXADOLINE).	Opioid Receptor Modulator	caution
ENOBY Comprehensive clinical and safety monograph for ENOBY (ENOBY).	Selective Androgen Receptor Modulator	caution
ERGAMISOL Comprehensive clinical and safety monograph for ERGAMISOL (ERGAMISOL).	Anthelmintic Immunomodulator	caution
EVISTA Comprehensive clinical and safety monograph for EVISTA (EVISTA).	Selective Estrogen Receptor Modulator	caution
FARESTON Comprehensive clinical and safety monograph for FARESTON (FARESTON).	Selective Estrogen Receptor Modulator	caution
FINGOLIMOD Comprehensive clinical and safety monograph for FINGOLIMOD (FINGOLIMOD).	Sphingosine 1-Phosphate Receptor Modulator	caution
FINGOLIMOD HYDROCHLORIDE Comprehensive clinical and safety monograph for FINGOLIMOD HYDROCHLORIDE (FINGOLIMOD HYDROCHLORIDE).	Sphingosine 1-Phosphate Receptor Modulator	caution
GILENYA Comprehensive clinical and safety monograph for GILENYA (GILENYA).	Sphingosine 1-Phosphate Receptor Modulator	caution
GLATIRAMER ACETATE No significant drug reactions Can cause immediate post-injection reaction (flushing chest pain palpitations).	Immunomodulator	safe
GLATOPA Comprehensive clinical and safety monograph for GLATOPA (GLATOPA).	Immunomodulator	caution
IMMPHENTIV Comprehensive clinical and safety monograph for IMMPHENTIV (IMMPHENTIV).	Immunomodulator	caution
JOENJA Comprehensive clinical and safety monograph for JOENJA (JOENJA).	Sphingosine 1-Phosphate Receptor Modulator	caution
LENALIDOMIDE Comprehensive clinical and safety monograph for LENALIDOMIDE (LENALIDOMIDE).	Immunomodulatory Agent	caution
MAYZENT Comprehensive clinical and safety monograph for MAYZENT (MAYZENT).	Sphingosine 1-Phosphate Receptor Modulator	caution
MILOPHENE Comprehensive clinical and safety monograph for MILOPHENE (MILOPHENE).	Selective Estrogen Receptor Modulator	caution
NOLVADEX Comprehensive clinical and safety monograph for NOLVADEX (NOLVADEX).	Selective Estrogen Receptor Modulator	caution
ORKAMBI Comprehensive clinical and safety monograph for ORKAMBI (ORKAMBI).	CFTR modulator	caution
OSPEMIFENE Comprehensive clinical and safety monograph for OSPEMIFENE (OSPEMIFENE).	Selective Estrogen Receptor Modulator (SERM)	caution
OSPHENA Comprehensive clinical and safety monograph for OSPHENA (OSPHENA).	Selective Estrogen Receptor Modulator (SERM)	caution
OZANIMOD Comprehensive clinical and safety monograph for OZANIMOD (OZANIMOD).	S1P Receptor Modulator	caution
PIASKY Comprehensive clinical and safety monograph for PIASKY (PIASKY).	Sphingosine 1-Phosphate Receptor Modulator	caution
POMALIDOMIDE Comprehensive clinical and safety monograph for POMALIDOMIDE (POMALIDOMIDE).	Immunomodulatory Agent	caution
POMALYST Comprehensive clinical and safety monograph for POMALYST (POMALYST).	Immunomodulatory Agent	caution
POMBILITI Comprehensive clinical and safety monograph for POMBILITI (POMBILITI).	Immunomodulatory Agent	caution
PONVORY Comprehensive clinical and safety monograph for PONVORY (PONVORY).	Sphingosine 1-Phosphate Receptor Modulator	caution
PROLEUKIN Comprehensive clinical and safety monograph for PROLEUKIN (PROLEUKIN).	Immunomodulator	caution
REBIF Comprehensive clinical and safety monograph for REBIF (REBIF).	Immunomodulator	caution
REVLIMID Comprehensive clinical and safety monograph for REVLIMID (REVLIMID).	Immunomodulatory Agent	caution
SIPONIMOD Comprehensive clinical and safety monograph for SIPONIMOD (SIPONIMOD).	S1P receptor modulator	caution
SOLTAMOX Comprehensive clinical and safety monograph for SOLTAMOX (SOLTAMOX).	Selective Estrogen Receptor Modulator	caution
TASCENSO ODT Comprehensive clinical and safety monograph for TASCENSO ODT (TASCENSO ODT).	Sphingosine 1-Phosphate Receptor Modulator	caution
TECFIDERA Comprehensive clinical and safety monograph for TECFIDERA (TECFIDERA).	Immunomodulator, Fumaric Acid Derivative	caution
TERIFLUNOMIDE Comprehensive clinical and safety monograph for TERIFLUNOMIDE (TERIFLUNOMIDE).	Immunomodulator	caution
THALIDOMIDE CNS depressants may enhance sedative effects Is a known human teratogen and requires strict pregnancy prevention program.	Immunomodulatory Agent	avoid
THALOMID Comprehensive clinical and safety monograph for THALOMID (THALOMID).	Immunomodulatory Agent	caution
TOREMIFENE CITRATE Comprehensive clinical and safety monograph for TOREMIFENE CITRATE (TOREMIFENE CITRATE).	Selective Estrogen Receptor Modulator	caution
TRIKAFTA (COPACKAGED) Comprehensive clinical and safety monograph for TRIKAFTA (COPACKAGED) (TRIKAFTA (COPACKAGED)).	CFTR Modulator	caution
TYSABRI Comprehensive clinical and safety monograph for TYSABRI (TYSABRI).	Multiple Sclerosis Immunomodulator	caution
ULESFIA Comprehensive clinical and safety monograph for ULESFIA (ULESFIA).	Progesterone Receptor Modulator	caution
VELSIPITY Comprehensive clinical and safety monograph for VELSIPITY (VELSIPITY).	Sphingosine 1-Phosphate Receptor Modulator	caution
VUMERITY Comprehensive clinical and safety monograph for VUMERITY (VUMERITY).	Fumarate Immunomodulator	caution
ZEPOSIA Comprehensive clinical and safety monograph for ZEPOSIA (ZEPOSIA).	Sphingosine 1-Phosphate Receptor Modulator	caution
ZOKINVY Comprehensive clinical and safety monograph for ZOKINVY (ZOKINVY).	CFTR Modulator	caution

This therapeutic registry is dynamically synthesized from professional clinical sources. Listing of a medication does not imply equivalence; refer to individual monographs for head-to-head pharmacological data.