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Registry Hub

Therapeutic Classification

snri Registry

Clinical reference for snri medications. Access safety monographs, dosing adjustments, and drug-drug interactions for all registered brand names and generics in this class.

Registered Medications (snri)

This therapeutic registry is dynamically synthesized from professional clinical sources. Listing of a medication does not imply equivalence; refer to individual monographs for head-to-head pharmacological data.

MedicationTherapeutic ClassMaternal Safety

CYMBALTA

Comprehensive clinical and safety monograph for CYMBALTA (CYMBALTA).

SNRI Antidepressant

caution

DESVENLAFAXINE

MAOIs can cause serotonin syndrome Can increase blood pressure and cause withdrawal symptoms upon discontinuation.

SNRI

caution

DESVENLAFAXINE SUCCINATE

MAOIs can cause serotonin syndrome Can increase blood pressure and cause withdrawal symptoms upon discontinuation.

SNRI

caution

DRIZALMA SPRINKLE

Comprehensive clinical and safety monograph for DRIZALMA SPRINKLE (DRIZALMA SPRINKLE).

SNRI Antidepressant

caution

DULOXETINE HYDROCHLORIDE

MAOIs can cause serotonin syndrome Can cause hepatotoxicity and increase suicidal thoughts and behaviors.

SNRI

caution

EFFEXOR

Comprehensive clinical and safety monograph for EFFEXOR (EFFEXOR).

SNRI Antidepressant

caution

EFFEXOR XR

Comprehensive clinical and safety monograph for EFFEXOR XR (EFFEXOR XR).

SNRI Antidepressant

caution

FETZIMA

Comprehensive clinical and safety monograph for FETZIMA (FETZIMA).

SNRI Antidepressant

caution

KHEDEZLA

Comprehensive clinical and safety monograph for KHEDEZLA (KHEDEZLA).

SNRI Antidepressant

caution

MILNACIPRAN HYDROCHLORIDE

Comprehensive clinical and safety monograph for MILNACIPRAN HYDROCHLORIDE (MILNACIPRAN HYDROCHLORIDE).

SNRI Antidepressant

caution

PRISTIQ

Comprehensive clinical and safety monograph for PRISTIQ (PRISTIQ).

SNRI Antidepressant

caution

SAVELLA

Comprehensive clinical and safety monograph for SAVELLA (SAVELLA).

SNRI Antidepressant

caution

Venlafaxine

SNRI used for depression, anxiety, and panic disorder. Large cohort data are largely reassuring for MCM but some studies suggest a small increase in risk of cardiovascular defects and postpartum hemorrhage. More prominent neonatal withdrawal syndrome than SSRIs due to norepinephrine reuptake inhibition — neonatal adaptation syndrome may be more severe and longer lasting. Pulmonary hypertension of the newborn (PPHN) risk similar to SSRIs (small absolute risk).

SNRI

caution

VENLAFAXINE BESYLATE

MAOIs can cause serotonin syndrome Can increase blood pressure and cause withdrawal symptoms upon discontinuation.

SNRI

caution

VENLAFAXINE HYDROCHLORIDE

MAOIs can cause serotonin syndrome Can increase blood pressure and cause withdrawal symptoms upon discontinuation.

SNRI

caution