Cetirizine

Clinical safety rating: safe

Animal studies have demonstrated safety

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Dosing & administration

Dosing varies by indication and patient profile. Always follow your institution's current prescribing guidelines.

Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Use during pregnancy

1st trimester	Safe. No consistent increase in congenital malformations.
2nd trimester	Safe.
3rd trimester	Safe.

Clinical note

Second-generation (non-sedating) antihistamine used for allergic rhinitis, urticaria, and pruritic conditions in pregnancy. Preferred over first-generation antihistamines due to minimal sedation and CNS penetration. Large registry data shows no significant increase in birth defects.

Breastfeeding

Safe. Low milk transfer; compatible with breastfeeding.

Warnings & precautions

When not to use it

Somnolence

Drug interactions

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