Comparative Pharmacology
Head-to-head clinical analysis: TRAVASOL 2 75 IN DEXTROSE 10 IN PLASTIC CONTAINER versus TRAVASOL 5 5 W ELECTROLYTES.
Peer-Reviewed Evidence
Head-to-head clinical analysis: TRAVASOL 2 75 IN DEXTROSE 10 IN PLASTIC CONTAINER versus TRAVASOL 5 5 W ELECTROLYTES.
TRAVASOL 2.75% IN DEXTROSE 10% IN PLASTIC CONTAINER vs TRAVASOL 5.5% W/ ELECTROLYTES
Comparing the clinical profiles, pharmacokinetic behaviors, and safety indices of these two therapeutic agents.
Travasol 2.75% in Dextrose 10% provides essential amino acids and caloric support via dextrose. Amino acids serve as substrates for protein synthesis and nitrogen balance, while dextrose provides glucose for energy metabolism. The combination is used for parenteral nutrition to maintain or restore positive nitrogen balance in patients unable to tolerate enteral nutrition.
TRAVASOL 5.5% W/ ELECTROLYTES is a parenteral nutritional solution providing amino acids and electrolytes. Amino acids serve as substrates for protein synthesis, while electrolytes maintain osmotic balance and support cellular functions. The solution bypasses gastrointestinal absorption, directly entering the bloodstream.
Intravenous infusion. 1000 mL to 3000 mL per day, typically infused at 1.2-1.5 g amino acids/kg/day; adjust based on metabolic needs and fluid status.
Intravenous infusion: 25-40 mL/kg/day (1.5-2.2 g amino acids/kg/day) as total parenteral nutrition; rate adjusted based on metabolic and clinical response.
None Documented
None Documented
Not applicable as a single entity. Components are endogenous substances. Dextrose has a half-life of minutes due to rapid insulin-mediated uptake. Amino acids have variable half-lives (minutes to hours) depending on individual amino acid and metabolic state.
2–3 hours for infused amino acids; clinical context: rapid clearance in normal renal function, prolonged in renal impairment.
TRAVASOL 2.75% IN DEXTROSE 10% is a combination of amino acids and dextrose. The amino acids are primarily metabolized and the nitrogen is excreted as urea in urine (renal, >90%). Dextrose is metabolized to CO2 and water; negligible biliary/fecal excretion.
Renal, >95% as amino acids and metabolites; negligible biliary/fecal.
Category C
Category C
Amino Acid Solution
Amino Acid Solution