EZETIMIBE AND SIMVASTATIN

Clinical safety rating: avoid

Strong CYP3A4 inhibitors (eg itraconazole) can significantly increase levels and risk of myopathy Can cause myopathy and rhabdomyolysis.

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Tablet 20 mg - Oral

Dosage form	TABLET
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

Strong CYP3A4 inhibitors (eg itraconazole) can significantly increase levels and risk of myopathy Can cause myopathy and rhabdomyolysis.

FDA category

Category Contraindicated

myalgia

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Clinical safety rating: avoid

Strong CYP3A4 inhibitors (eg itraconazole) can significantly increase levels and risk of myopathy Can cause myopathy and rhabdomyolysis.

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Tablet 20 mg - Oral

Dosage form	TABLET
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

Strong CYP3A4 inhibitors (eg itraconazole) can significantly increase levels and risk of myopathy Can cause myopathy and rhabdomyolysis.

FDA category

Category Contraindicated

myalgia

Loading safety data…