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Dosing & administration
Dosing varies by indication and patient profile. Always follow your institution's current prescribing guidelines.
Renal impairment
Consult protocols for adjustment.
Liver impairment
Consult protocols for adjustment.
Use during pregnancy
1st trimester
Safe. No established teratogenicity.
2nd trimester
Safe.
3rd trimester
Safe. Used IV for acute severe hypertension. Monitor for maternal hypotension and fetal heart rate changes.
Clinical note
Parenteral vasodilator used for acute treatment of severe-range blood pressures (≥160/110 mmHg) in pregnancy and postpartum. Extensively used for decades with no established teratogenicity. IV labetalol and oral/IV nifedipine are now often preferred for acute management, but hydralazine remains a reasonable alternative and is widely available in low-resource settings. Risk of maternal hypotension and reflex tachycardia with IV use.
Breastfeeding
Safe. Compatible with breastfeeding; low milk transfer.
