IBRUTINIB

Clinical safety rating: avoid

Contraindicated (not allowed)

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Capsule 140 mg - Oral

Dosage form	CAPSULE
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

Strong CYP3A4 inhibitors may increase levels and inducers may decrease levels Can cause bleeding infections and atrial fibrillation.

Bleeding

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Clinical safety rating: avoid

Contraindicated (not allowed)

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Capsule 140 mg - Oral

Dosage form	CAPSULE
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

Strong CYP3A4 inhibitors may increase levels and inducers may decrease levels Can cause bleeding infections and atrial fibrillation.