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Dosing & administration
Dosing varies by indication and patient profile. Always follow your institution's current prescribing guidelines.
Renal impairment
Consult protocols for adjustment.
Liver impairment
Consult protocols for adjustment.
Use during pregnancy
1st trimester
Safe. No consistent link to structural defects.
2nd trimester
Safe. Effective blood pressure control.
3rd trimester
Safe. Monitor neonate for bradycardia, hypoglycemia, and respiratory depression at delivery, especially at high doses.
Clinical note
First-line oral antihypertensive for chronic hypertension in pregnancy and acute management of severe-range blood pressures (≥160/110 mmHg) alongside IV formulations. Extensive safety data; no consistent link to structural defects. Neonatal monitoring recommended when used at delivery.
Breastfeeding
Safe. Low levels excreted in breast milk; compatible with breastfeeding.
