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MEDROXYPROGESTERONE ACETATE | Drug Overview & Clinical Reference

Progestin/Discontinued

MEDROXYPROGESTERONE ACETATE

MEDROXYPROGESTERONE ACETATE

Clinical safety rating: avoid

Positive evidence of fetus risks but benefits may outweigh risks in some cases

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Dosing & administration

Capsule 100 mg - Oral

Dosage form	INJECTABLE
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Use during pregnancy

1st trimester	Consult provider
2nd trimester	Consult provider
3rd trimester	Consult provider

Clinical note

CYP3A4 inducers can decrease efficacy Can cause thromboembolic disorders.

Warnings & precautions

When not to use it

Weight gain

Drug interactions

Loading safety data…

This overview is compiled from peer-reviewed clinical sources and FDA labeling. It's here to support — not replace — clinical judgment. Always verify dosing against your institution's current protocols before prescribing.

On this page

How it works Dosing & administration Use during pregnancy Warnings & precautions Drug interactions

External sources

DailyMed (NIH) PubMed OpenFDA