METHOTREXATE LPF

Clinical safety rating: avoid

NSAIDs and probenecid can decrease renal excretion and increase levels Can cause myelosuppression and hepatotoxicity.

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Tablet 2.5 mg - Oral

Dosage form	INJECTABLE
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

NSAIDs and probenecid can decrease renal excretion and increase levels Can cause myelosuppression and hepatotoxicity.

FDA category

Category Contraindicated

Myelosuppression

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Clinical safety rating: avoid

NSAIDs and probenecid can decrease renal excretion and increase levels Can cause myelosuppression and hepatotoxicity.

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Tablet 2.5 mg - Oral

Dosage form	INJECTABLE
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

NSAIDs and probenecid can decrease renal excretion and increase levels Can cause myelosuppression and hepatotoxicity.

FDA category

Category Contraindicated

Myelosuppression

Loading safety data…