METHYLPREDNISOLONE ACETATE

Clinical safety rating: avoid

CYP3A4 inducers (eg phenytoin) may decrease efficacy and inhibitors may increase effects Can cause hyperglycemia and adrenal suppression with prolonged use.

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Dosing & administration

Tablet 5 mg - Oral

Dosage form	INJECTABLE
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Use during pregnancy

1st trimester	Consult provider
2nd trimester	Consult provider
3rd trimester	Consult provider

Clinical note

CYP3A4 inducers (eg phenytoin) may decrease efficacy and inhibitors may increase effects Can cause hyperglycemia and adrenal suppression with prolonged use.

FDA category

Category Positive

Warnings & precautions

When not to use it

Hyperglycemia

Drug interactions

Loading safety data…

METHYLPREDNISOLONE ACETATE

Clinical safety rating: avoid

CYP3A4 inducers (eg phenytoin) may decrease efficacy and inhibitors may increase effects Can cause hyperglycemia and adrenal suppression with prolonged use.

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Dosing & administration

Tablet 5 mg - Oral

Dosage form	INJECTABLE
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Use during pregnancy

1st trimester	Consult provider
2nd trimester	Consult provider
3rd trimester	Consult provider

Clinical note

CYP3A4 inducers (eg phenytoin) may decrease efficacy and inhibitors may increase effects Can cause hyperglycemia and adrenal suppression with prolonged use.

FDA category

Category Positive

Warnings & precautions

When not to use it

Hyperglycemia

Drug interactions

Loading safety data…