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Clinical Notice:Calculations must be re-checked and should not be used alone to guide patient care, nor should they substitute for professional clinical judgment. OpiCalc is an auxiliary reference tool for qualified healthcare professionals.

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NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE | Drug Overview & Clinical Reference

Sympathomimetic/Over-the-counter

NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE

NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE

Clinical safety rating: safe

Animal studies have demonstrated safety

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Dosing & administration

Tablet 60 mg - Oral

Dosage form	TABLET, EXTENDED RELEASE
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Use during pregnancy

1st trimester	Consult provider
2nd trimester	Consult provider
3rd trimester	Consult provider

Clinical note

MAOIs can cause hypertensive crisis Can cause insomnia and tachycardia.

Warnings & precautions

When not to use it

dizziness

Drug interactions

Loading safety data…

This overview is compiled from peer-reviewed clinical sources and FDA labeling. It's here to support — not replace — clinical judgment. Always verify dosing against your institution's current protocols before prescribing.

On this page

How it works Dosing & administration Use during pregnancy Warnings & precautions Drug interactions

External sources

DailyMed (NIH) PubMed OpenFDA