Oseltamivir

Clinical safety rating: safe

Animal studies have demonstrated safety

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Dosing & administration

Dosing varies by indication and patient profile. Always follow your institution's current prescribing guidelines.

Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Use during pregnancy

1st trimester	Safe. Treat influenza promptly — pregnancy worsens severity.
2nd trimester	Safe.
3rd trimester	Safe. Highest maternal morbidity risk in T3.

Clinical note

Recommended for treatment of influenza in pregnancy regardless of trimester. Pregnant women are at high risk for severe influenza (pneumonia, preterm birth, maternal death). Benefits clearly outweigh risks. Treatment should be initiated within 48 hours of symptom onset. Prophylaxis is also appropriate after significant exposure. No evidence of teratogenicity. Influenza vaccination during pregnancy is separately recommended by ACOG/CDC.

Breastfeeding

Safe. Compatible with breastfeeding. Infant receives some drug through milk, potentially providing therapeutic levels — this may be beneficial if infant is also symptomatic.

Warnings & precautions

When not to use it

vomiting

Drug interactions

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