Venlafaxine
SNRI used for depression, anxiety, and panic disorder. Large cohort data are largely reassuring for MCM but some studies suggest a small increase in risk of cardiovascular defects and postpartum hemorrhage. More prominent neonatal withdrawal syndrome than SSRIs due to norepinephrine reuptake inhibition — neonatal adaptation syndrome may be more severe and longer lasting. Pulmonary hypertension of the newborn (PPHN) risk similar to SSRIs (small absolute risk).
