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Medication	Therapeutic Class	Generic Mapping	Safety
ZINC CHLORIDE Comprehensive clinical and safety monograph for ZINC CHLORIDE (ZINC CHLORIDE).	Mineral Supplement	ZINC CHLORIDE	caution
ZINC CHLORIDE IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ZINC CHLORIDE IN PLASTIC CONTAINER (ZINC CHLORIDE IN PLASTIC CONTAINER).	Mineral Supplement	ZINC CHLORIDE IN PLASTIC CONTAINER	caution
ZINC SULFATE Comprehensive clinical and safety monograph for ZINC SULFATE (ZINC SULFATE).	Mineral Supplement	ZINC SULFATE	caution
ZINC SULFATE HEPTAHYDRATE, CUPRIC SULFATE, MANGANESE SULFATE, SELENIOUS ACID Comprehensive clinical and safety monograph for ZINC SULFATE HEPTAHYDRATE, CUPRIC SULFATE, MANGANESE SULFATE, SELENIOUS ACID (ZINC SULFATE HEPTAHYDRATE, CUPRIC SULFATE, MANGANESE SULFATE, SELENIOUS ACID).	Unclassified (Manual Review Required)	ZINC SULFATE HEPTAHYDRATE, CUPRIC SULFATE, MANGANESE SULFATE, SELENIOUS ACID	caution
ZINECARD Comprehensive clinical and safety monograph for ZINECARD (ZINECARD).	Cardioprotectant	ZINECARD	caution
ZINGO Comprehensive clinical and safety monograph for ZINGO (ZINGO).	Vaccine	ZINGO	caution
ZINPLAVA Comprehensive clinical and safety monograph for ZINPLAVA (ZINPLAVA).	Monoclonal Antibody	ZINPLAVA	caution
ZIOPTAN Comprehensive clinical and safety monograph for ZIOPTAN (ZIOPTAN).	Prostaglandin Analog	ZIOPTAN	caution
ZIPAN-25 Comprehensive clinical and safety monograph for ZIPAN-25 (ZIPAN-25).	Opioid Analgesic	ZIPAN-25	caution
ZIPAN-50 Comprehensive clinical and safety monograph for ZIPAN-50 (ZIPAN-50).	Opioid Analgesic	ZIPAN-50	caution
ZIPRASIDONE HYDROCHLORIDE Other drugs that prolong the QT interval are contraindicated Can cause QT prolongation and rash.	Atypical Antipsychotic	ZIPRASIDONE HYDROCHLORIDE	safe
ZIPRASIDONE MESYLATE Other drugs that prolong the QT interval are contraindicated Can cause QT prolongation and rash.	Atypical Antipsychotic	ZIPRASIDONE MESYLATE	safe
ZIPSOR Comprehensive clinical and safety monograph for ZIPSOR (ZIPSOR).	NSAID	ZIPSOR	caution
ZIRABEV Comprehensive clinical and safety monograph for ZIRABEV (ZIRABEV).	Monoclonal Antibody	ZIRABEV	caution
ZIRGAN Comprehensive clinical and safety monograph for ZIRGAN (ZIRGAN).	Antiviral	ZIRGAN	caution
ZITHROMAX Comprehensive clinical and safety monograph for ZITHROMAX (ZITHROMAX).	Macrolide Antibiotic	ZITHROMAX	caution
ZITUVIMET Comprehensive clinical and safety monograph for ZITUVIMET (ZITUVIMET).	Antidiabetic Combination	ZITUVIMET	caution
ZITUVIMET XR Comprehensive clinical and safety monograph for ZITUVIMET XR (ZITUVIMET XR).	Antidiabetic Combination	ZITUVIMET XR	caution
ZITUVIO Comprehensive clinical and safety monograph for ZITUVIO (ZITUVIO).	DPP-4 Inhibitor	ZITUVIO	caution
ZMAX Comprehensive clinical and safety monograph for ZMAX (ZMAX).	Macrolide Antibiotic	ZMAX	caution
ZOCOR Comprehensive clinical and safety monograph for ZOCOR (ZOCOR).	Statin Antihyperlipidemic	ZOCOR	caution
ZOFRAN Comprehensive clinical and safety monograph for ZOFRAN (ZOFRAN).	Antiemetic (5-HT3 Antagonist)	ZOFRAN	caution
ZOFRAN AND DEXTROSE IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ZOFRAN AND DEXTROSE IN PLASTIC CONTAINER (ZOFRAN AND DEXTROSE IN PLASTIC CONTAINER).	Antiemetic (5-HT3 Antagonist)	ZOFRAN AND DEXTROSE IN PLASTIC CONTAINER	caution
ZOFRAN ODT Comprehensive clinical and safety monograph for ZOFRAN ODT (ZOFRAN ODT).	Antiemetic (5-HT3 Antagonist)	ZOFRAN ODT	caution
ZOFRAN PRESERVATIVE FREE Comprehensive clinical and safety monograph for ZOFRAN PRESERVATIVE FREE (ZOFRAN PRESERVATIVE FREE).	Antiemetic (5-HT3 Antagonist)	ZOFRAN PRESERVATIVE FREE	caution
ZOHYDRO ER Comprehensive clinical and safety monograph for ZOHYDRO ER (ZOHYDRO ER).	Opioid Analgesic	ZOHYDRO ER	caution
ZOKINVY Comprehensive clinical and safety monograph for ZOKINVY (ZOKINVY).	CFTR Modulator	ZOKINVY	caution
ZOLADEX Comprehensive clinical and safety monograph for ZOLADEX (ZOLADEX).	GnRH Agonist	ZOLADEX	caution
ZOLEDRONIC Comprehensive clinical and safety monograph for ZOLEDRONIC (ZOLEDRONIC).	Bisphosphonate	ZOLEDRONIC	caution
ZOLEDRONIC ACID Nephrotoxic drugs may increase risk of renal impairment Can cause renal impairment and osteonecrosis of the jaw.	Bisphosphonate	ZOLEDRONIC ACID	avoid
ZOLINZA Comprehensive clinical and safety monograph for ZOLINZA (ZOLINZA).	Histone Deacetylase Inhibitor	ZOLINZA	caution
ZOLMITRIPTAN Other 5-HT1 agonists and MAOIs can have additive effects Contraindicated in ischemic heart disease and uncontrolled hypertension.	5-HT1 Agonist	ZOLMITRIPTAN	avoid
ZOLOFT Comprehensive clinical and safety monograph for ZOLOFT (ZOLOFT).	SSRI Antidepressant	ZOLOFT	caution
ZOLPIDEM TARTRATE CNS depressants including alcohol increase sedation risk Can cause complex sleep behaviors like sleep-driving.	Non-Benzodiazepine Hypnotic	ZOLPIDEM TARTRATE	safe
ZOLPIMIST Comprehensive clinical and safety monograph for ZOLPIMIST (ZOLPIMIST).	Sedative-Hypnotic (Non-benzodiazepine)	ZOLPIMIST	caution
ZOLYMBUS Comprehensive clinical and safety monograph for ZOLYMBUS (ZOLYMBUS).	Enzyme Replacement Therapy	ZOLYMBUS	caution
ZOMACTON Comprehensive clinical and safety monograph for ZOMACTON (ZOMACTON).	Growth Hormone	ZOMACTON	caution
ZOMETA Comprehensive clinical and safety monograph for ZOMETA (ZOMETA).	Bisphosphonate	ZOMETA	caution
ZOMIG Comprehensive clinical and safety monograph for ZOMIG (ZOMIG).	Triptan Antimigraine	ZOMIG	caution
ZOMIG-ZMT Comprehensive clinical and safety monograph for ZOMIG-ZMT (ZOMIG-ZMT).	Triptan Antimigraine	ZOMIG-ZMT	caution
ZONALON Comprehensive clinical and safety monograph for ZONALON (ZONALON).	Topical Antipruritic (Tricyclic Antidepressant)	ZONALON	caution
ZONEGRAN Comprehensive clinical and safety monograph for ZONEGRAN (ZONEGRAN).	Anticonvulsant	ZONEGRAN	caution
ZONISADE Comprehensive clinical and safety monograph for ZONISADE (ZONISADE).	Anticonvulsant	ZONISADE	caution
ZONISAMIDE Strong CYP3A4 inducers may decrease levels Can cause oligohydrosis and hyperthermia in children and metabolic acidosis.	Anticonvulsant	ZONISAMIDE	caution
ZONTIVITY Comprehensive clinical and safety monograph for ZONTIVITY (ZONTIVITY).	Antiplatelet Agent	ZONTIVITY	caution
ZORBTIVE Comprehensive clinical and safety monograph for ZORBTIVE (ZORBTIVE).	Growth Hormone	ZORBTIVE	caution
ZORTRESS Comprehensive clinical and safety monograph for ZORTRESS (ZORTRESS).	Immunosuppressant	ZORTRESS	caution
ZORVOLEX Comprehensive clinical and safety monograph for ZORVOLEX (ZORVOLEX).	NSAID	ZORVOLEX	caution
ZORYVE Comprehensive clinical and safety monograph for ZORYVE (ZORYVE).	PDE4 Inhibitor	ZORYVE	caution
ZOSYN Comprehensive clinical and safety monograph for ZOSYN (ZOSYN).	Antibiotic	ZOSYN	caution

ZINC CHLORIDE

Comprehensive clinical and safety monograph for ZINC CHLORIDE (ZINC CHLORIDE).

Mineral Supplement

caution

ZINC CHLORIDE IN PLASTIC CONTAINER

Comprehensive clinical and safety monograph for ZINC CHLORIDE IN PLASTIC CONTAINER (ZINC CHLORIDE IN PLASTIC CONTAINER).

Mineral Supplement

caution

ZINC SULFATE

Comprehensive clinical and safety monograph for ZINC SULFATE (ZINC SULFATE).

Mineral Supplement

caution

ZINC SULFATE HEPTAHYDRATE, CUPRIC SULFATE, MANGANESE SULFATE, SELENIOUS ACID

Comprehensive clinical and safety monograph for ZINC SULFATE HEPTAHYDRATE, CUPRIC SULFATE, MANGANESE SULFATE, SELENIOUS ACID (ZINC SULFATE HEPTAHYDRATE, CUPRIC SULFATE, MANGANESE SULFATE, SELENIOUS ACID).

Unclassified (Manual Review Required)

caution

ZINECARD

Comprehensive clinical and safety monograph for ZINECARD (ZINECARD).

Cardioprotectant

caution

ZINGO

Comprehensive clinical and safety monograph for ZINGO (ZINGO).

Vaccine

caution

ZINPLAVA

Comprehensive clinical and safety monograph for ZINPLAVA (ZINPLAVA).

Monoclonal Antibody

caution

ZIOPTAN

Comprehensive clinical and safety monograph for ZIOPTAN (ZIOPTAN).

Prostaglandin Analog

caution

ZIPAN-25

Comprehensive clinical and safety monograph for ZIPAN-25 (ZIPAN-25).

Opioid Analgesic

caution

ZIPAN-50

Comprehensive clinical and safety monograph for ZIPAN-50 (ZIPAN-50).

Opioid Analgesic

caution

ZIPRASIDONE HYDROCHLORIDE

Other drugs that prolong the QT interval are contraindicated Can cause QT prolongation and rash.

Atypical Antipsychotic

safe

ZIPRASIDONE MESYLATE

Other drugs that prolong the QT interval are contraindicated Can cause QT prolongation and rash.

Atypical Antipsychotic

safe

ZIPSOR

Comprehensive clinical and safety monograph for ZIPSOR (ZIPSOR).

NSAID

caution

ZIRABEV

Comprehensive clinical and safety monograph for ZIRABEV (ZIRABEV).

Monoclonal Antibody

caution

ZIRGAN

Comprehensive clinical and safety monograph for ZIRGAN (ZIRGAN).

Antiviral

caution

ZITHROMAX

Comprehensive clinical and safety monograph for ZITHROMAX (ZITHROMAX).

Macrolide Antibiotic

caution

ZITUVIMET

Comprehensive clinical and safety monograph for ZITUVIMET (ZITUVIMET).

Antidiabetic Combination

caution

ZITUVIMET XR

Comprehensive clinical and safety monograph for ZITUVIMET XR (ZITUVIMET XR).

Antidiabetic Combination

caution

ZITUVIO

Comprehensive clinical and safety monograph for ZITUVIO (ZITUVIO).

DPP-4 Inhibitor

caution

ZMAX

Comprehensive clinical and safety monograph for ZMAX (ZMAX).

Macrolide Antibiotic

caution

ZOCOR

Comprehensive clinical and safety monograph for ZOCOR (ZOCOR).

Statin Antihyperlipidemic

caution

ZOFRAN

Comprehensive clinical and safety monograph for ZOFRAN (ZOFRAN).

Antiemetic (5-HT3 Antagonist)

caution

ZOFRAN AND DEXTROSE IN PLASTIC CONTAINER

Comprehensive clinical and safety monograph for ZOFRAN AND DEXTROSE IN PLASTIC CONTAINER (ZOFRAN AND DEXTROSE IN PLASTIC CONTAINER).

Antiemetic (5-HT3 Antagonist)

caution

ZOFRAN ODT

Comprehensive clinical and safety monograph for ZOFRAN ODT (ZOFRAN ODT).

Antiemetic (5-HT3 Antagonist)

caution

ZOFRAN PRESERVATIVE FREE

Comprehensive clinical and safety monograph for ZOFRAN PRESERVATIVE FREE (ZOFRAN PRESERVATIVE FREE).

Antiemetic (5-HT3 Antagonist)

caution

ZOHYDRO ER

Comprehensive clinical and safety monograph for ZOHYDRO ER (ZOHYDRO ER).

Opioid Analgesic

caution

ZOKINVY

Comprehensive clinical and safety monograph for ZOKINVY (ZOKINVY).

CFTR Modulator

caution

ZOLADEX

Comprehensive clinical and safety monograph for ZOLADEX (ZOLADEX).

GnRH Agonist

caution

ZOLEDRONIC

Comprehensive clinical and safety monograph for ZOLEDRONIC (ZOLEDRONIC).

Bisphosphonate

caution

ZOLEDRONIC ACID

Nephrotoxic drugs may increase risk of renal impairment Can cause renal impairment and osteonecrosis of the jaw.

Bisphosphonate

avoid

ZOLINZA

Comprehensive clinical and safety monograph for ZOLINZA (ZOLINZA).

Histone Deacetylase Inhibitor

caution

ZOLMITRIPTAN

Other 5-HT1 agonists and MAOIs can have additive effects Contraindicated in ischemic heart disease and uncontrolled hypertension.

5-HT1 Agonist

avoid

ZOLOFT

Comprehensive clinical and safety monograph for ZOLOFT (ZOLOFT).

SSRI Antidepressant

caution

ZOLPIDEM TARTRATE

CNS depressants including alcohol increase sedation risk Can cause complex sleep behaviors like sleep-driving.

Non-Benzodiazepine Hypnotic

safe

ZOLPIMIST

Comprehensive clinical and safety monograph for ZOLPIMIST (ZOLPIMIST).

Sedative-Hypnotic (Non-benzodiazepine)

caution

ZOLYMBUS

Comprehensive clinical and safety monograph for ZOLYMBUS (ZOLYMBUS).

Enzyme Replacement Therapy

caution

ZOMACTON

Comprehensive clinical and safety monograph for ZOMACTON (ZOMACTON).

Growth Hormone

caution

ZOMETA

Comprehensive clinical and safety monograph for ZOMETA (ZOMETA).

Bisphosphonate

caution

ZOMIG

Comprehensive clinical and safety monograph for ZOMIG (ZOMIG).

Triptan Antimigraine

caution

ZOMIG-ZMT

Comprehensive clinical and safety monograph for ZOMIG-ZMT (ZOMIG-ZMT).

Triptan Antimigraine

caution

ZONALON

Comprehensive clinical and safety monograph for ZONALON (ZONALON).

Topical Antipruritic (Tricyclic Antidepressant)

caution

ZONEGRAN

Comprehensive clinical and safety monograph for ZONEGRAN (ZONEGRAN).

Anticonvulsant

caution

ZONISADE

Comprehensive clinical and safety monograph for ZONISADE (ZONISADE).

Anticonvulsant

caution

ZONISAMIDE

Strong CYP3A4 inducers may decrease levels Can cause oligohydrosis and hyperthermia in children and metabolic acidosis.

Anticonvulsant

caution

ZONTIVITY

Comprehensive clinical and safety monograph for ZONTIVITY (ZONTIVITY).

Antiplatelet Agent

caution

ZORBTIVE

Comprehensive clinical and safety monograph for ZORBTIVE (ZORBTIVE).

Growth Hormone

caution

ZORTRESS

Comprehensive clinical and safety monograph for ZORTRESS (ZORTRESS).

Immunosuppressant

caution

ZORVOLEX

Comprehensive clinical and safety monograph for ZORVOLEX (ZORVOLEX).

NSAID

caution

ZORYVE

Comprehensive clinical and safety monograph for ZORYVE (ZORYVE).

PDE4 Inhibitor

caution

ZOSYN

Comprehensive clinical and safety monograph for ZOSYN (ZOSYN).

Antibiotic

caution

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