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8,240 Clinical Drug Overviews

Medication	Therapeutic Class	Generic Mapping	Safety
IRBESARTAN AND HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus.	ARB	IRBESARTAN AND HYDROCHLOROTHIAZIDE	avoid
IRBESARTAN HYDROCHLOROTHIAZIDE NSAIDs may diminish the antihypertensive effect Lithium levels may be increased Use in pregnancy can cause injury and death to the developing fetus.	ARB	IRBESARTAN HYDROCHLOROTHIAZIDE	avoid
IRESSA Comprehensive clinical and safety monograph for IRESSA (IRESSA).	EGFR Tyrosine Kinase Inhibitor	IRESSA	caution
IRINOTECAN HYDROCHLORIDE Strong CYP3A4 inducers or inhibitors may alter levels Can cause severe delayed diarrhea and myelosuppression.	Topoisomerase Inhibitor	IRINOTECAN HYDROCHLORIDE	avoid
IRON DEXTRAN Comprehensive clinical and safety monograph for IRON DEXTRAN (IRON DEXTRAN).	Iron Replacement	IRON DEXTRAN	caution
IRON SUCROSE Comprehensive clinical and safety monograph for IRON SUCROSE (IRON SUCROSE).	Intravenous Iron Replacement	IRON SUCROSE	caution
Iron Supplements (Ferrous Sulfate) Essential supplementation in pregnancy. Iron deficiency anaemia is the most common nutritional deficiency in pregnancy worldwide. WHO recommends 30–60 mg elemental iron daily for all pregnant women, higher doses for anaemia. No teratogenicity — iron is an essential micronutrient. Common side effects include constipation, nausea, and dark stools. Vitamin C coadministration enhances absorption. Avoid taking with calcium, tea, or coffee.	Oral Iron Supplement		safe
IRRIGATING SOLUTION G IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for IRRIGATING SOLUTION G IN PLASTIC CONTAINER (IRRIGATING SOLUTION G IN PLASTIC CONTAINER).	Irrigating Solution	IRRIGATING SOLUTION G IN PLASTIC CONTAINER	caution
ISENTRESS Comprehensive clinical and safety monograph for ISENTRESS (ISENTRESS).	HIV Integrase Inhibitor	ISENTRESS	caution
ISENTRESS HD Comprehensive clinical and safety monograph for ISENTRESS HD (ISENTRESS HD).	HIV Integrase Inhibitor	ISENTRESS HD	caution
ISIBLOOM Comprehensive clinical and safety monograph for ISIBLOOM (ISIBLOOM).	Oral Contraceptive	ISIBLOOM	caution
ISMELIN Comprehensive clinical and safety monograph for ISMELIN (ISMELIN).	Adrenergic Neuron Blocker Antihypertensive	ISMELIN	caution
ISMO Comprehensive clinical and safety monograph for ISMO (ISMO).	Nitrate Vasodilator	ISMO	caution
ISMOTIC Comprehensive clinical and safety monograph for ISMOTIC (ISMOTIC).	Osmotic Diuretic	ISMOTIC	caution
ISOCAINE HYDROCHLORIDE Comprehensive clinical and safety monograph for ISOCAINE HYDROCHLORIDE (ISOCAINE HYDROCHLORIDE).	Local Anesthetic	ISOCAINE HYDROCHLORIDE	caution
ISOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN Comprehensive clinical and safety monograph for ISOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN (ISOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN).	Local Anesthetic with Vasoconstrictor	ISOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN	caution
ISOCLOR Comprehensive clinical and safety monograph for ISOCLOR (ISOCLOR).	Antihistamine/Decongestant Combination	ISOCLOR	caution
ISOETHARINE HYDROCHLORIDE Comprehensive clinical and safety monograph for ISOETHARINE HYDROCHLORIDE (ISOETHARINE HYDROCHLORIDE).	Beta-2 Adrenergic Agonist	ISOETHARINE HYDROCHLORIDE	caution
ISOETHARINE HYDROCHLORIDE S/F Comprehensive clinical and safety monograph for ISOETHARINE HYDROCHLORIDE S/F (ISOETHARINE HYDROCHLORIDE S/F).	Beta-2 Adrenergic Agonist	ISOETHARINE HYDROCHLORIDE S/F	caution
ISOETHARINE MESYLATE Comprehensive clinical and safety monograph for ISOETHARINE MESYLATE (ISOETHARINE MESYLATE).	Beta-2 Adrenergic Agonist	ISOETHARINE MESYLATE	caution
ISOFLURANE Comprehensive clinical and safety monograph for ISOFLURANE (ISOFLURANE).	Inhalational Anesthetic	ISOFLURANE	caution
ISOLYTE E IN DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE E IN DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE E IN DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution with Dextrose	ISOLYTE E IN DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE E IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE E IN PLASTIC CONTAINER (ISOLYTE E IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE E IN PLASTIC CONTAINER	caution
ISOLYTE E W/ DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE E W/ DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE E W/ DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution with Dextrose	ISOLYTE E W/ DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE H IN DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE H IN DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE H IN DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution with Dextrose	ISOLYTE H IN DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE H W/ DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE H W/ DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE H W/ DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE H W/ DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE M IN DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE M IN DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE M IN DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE M IN DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE M W/ DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE M W/ DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE M W/ DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE M W/ DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE P IN DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE P IN DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE P IN DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE P IN DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE P W/ DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE P W/ DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE P W/ DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE P W/ DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE R IN DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE R IN DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE R IN DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE R IN DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE R W/ DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE R W/ DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE R W/ DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE R W/ DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE S IN DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE S IN DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE S IN DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE S IN DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISOLYTE S IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE S IN PLASTIC CONTAINER (ISOLYTE S IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE S IN PLASTIC CONTAINER	caution
ISOLYTE S PH 7.4 IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE S PH 7.4 IN PLASTIC CONTAINER (ISOLYTE S PH 7.4 IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE S PH 7.4 IN PLASTIC CONTAINER	caution
ISOLYTE S W/ DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for ISOLYTE S W/ DEXTROSE 5% IN PLASTIC CONTAINER (ISOLYTE S W/ DEXTROSE 5% IN PLASTIC CONTAINER).	Intravenous Electrolyte Solution	ISOLYTE S W/ DEXTROSE 5% IN PLASTIC CONTAINER	caution
ISONIAZID Inhibits CYP450 enzymes increasing levels of many drugs (eg phenytoin) Can cause severe hepatotoxicity and peripheral neuropathy.	Antimycobacterial	ISONIAZID	safe
ISOPAQUE 280 Comprehensive clinical and safety monograph for ISOPAQUE 280 (ISOPAQUE 280).	Radiocontrast Agent	ISOPAQUE 280	caution
ISOPAQUE 440 Comprehensive clinical and safety monograph for ISOPAQUE 440 (ISOPAQUE 440).	Radiocontrast Agent	ISOPAQUE 440	caution
ISOPROTERENOL HYDROCHLORIDE Comprehensive clinical and safety monograph for ISOPROTERENOL HYDROCHLORIDE (ISOPROTERENOL HYDROCHLORIDE).	Beta-Adrenergic Agonist	ISOPROTERENOL HYDROCHLORIDE	caution
ISOPTIN Comprehensive clinical and safety monograph for ISOPTIN (ISOPTIN).	Calcium Channel Blocker	ISOPTIN	caution
ISOPTO ATROPINE Comprehensive clinical and safety monograph for ISOPTO ATROPINE (ISOPTO ATROPINE).	Ophthalmic Anticholinergic	ISOPTO ATROPINE	caution
ISOPTO CARPINE Comprehensive clinical and safety monograph for ISOPTO CARPINE (ISOPTO CARPINE).	Ophthalmic Cholinergic Agonist	ISOPTO CARPINE	caution
ISOPTO CETAMIDE Comprehensive clinical and safety monograph for ISOPTO CETAMIDE (ISOPTO CETAMIDE).	Ophthalmic Antibiotic	ISOPTO CETAMIDE	caution
ISOPTO CETAPRED Comprehensive clinical and safety monograph for ISOPTO CETAPRED (ISOPTO CETAPRED).	Ophthalmic Antibiotic/Corticosteroid Combination	ISOPTO CETAPRED	caution
ISORDIL Comprehensive clinical and safety monograph for ISORDIL (ISORDIL).	Nitrate Vasodilator	ISORDIL	caution
ISOSORBIDE DINITRATE Phosphodiesterase inhibitors (eg sildenafil) can cause severe hypotension Can cause tolerance with continuous use and severe headaches.	Nitrate	ISOSORBIDE DINITRATE	safe
ISOSORBIDE DINITRATE AND HYDRALAZINE HYDROCHLORIDE Phosphodiesterase inhibitors (eg sildenafil) can cause severe hypotension Can cause tolerance with continuous use and severe headaches.	Nitrate	ISOSORBIDE DINITRATE AND HYDRALAZINE HYDROCHLORIDE	safe
ISOSORBIDE MONONITRATE Phosphodiesterase inhibitors (eg sildenafil) can cause severe hypotension Can cause tolerance with continuous use and severe headaches.	Nitrate	ISOSORBIDE MONONITRATE	safe
ISOSULFAN BLUE Comprehensive clinical and safety monograph for ISOSULFAN BLUE (ISOSULFAN BLUE).	Diagnostic Dye	ISOSULFAN BLUE	caution

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