ISOTRETINOIN No significant drug interactions Highly teratogenic and can cause severe skin irritation. | Retinoid | ISOTRETINOIN | avoid |
ISOVUE-128 Comprehensive clinical and safety monograph for ISOVUE-128 (ISOVUE-128). | Contrast Media | ISOVUE-128 | caution |
ISOVUE-200 Comprehensive clinical and safety monograph for ISOVUE-200 (ISOVUE-200). | Contrast Media | ISOVUE-200 | caution |
ISOVUE-250 Comprehensive clinical and safety monograph for ISOVUE-250 (ISOVUE-250). | Contrast Media | ISOVUE-250 | caution |
ISOVUE-300 Comprehensive clinical and safety monograph for ISOVUE-300 (ISOVUE-300). | Contrast Media | ISOVUE-300 | caution |
ISOVUE-370 Comprehensive clinical and safety monograph for ISOVUE-370 (ISOVUE-370). | Contrast Media | ISOVUE-370 | caution |
ISOVUE-M 200 Comprehensive clinical and safety monograph for ISOVUE-M 200 (ISOVUE-M 200). | Contrast Media | ISOVUE-M 200 | caution |
ISOVUE-M 300 Comprehensive clinical and safety monograph for ISOVUE-M 300 (ISOVUE-M 300). | Contrast Media | ISOVUE-M 300 | caution |
ISRADIPINE Comprehensive clinical and safety monograph for ISRADIPINE (ISRADIPINE). | Calcium Channel Blocker | ISRADIPINE | caution |
ISTALOL Comprehensive clinical and safety monograph for ISTALOL (ISTALOL). | Beta-Blocker Ophthalmic | ISTALOL | caution |
ISTODAX Comprehensive clinical and safety monograph for ISTODAX (ISTODAX). | HDAC Inhibitor | ISTODAX | caution |
ISTURISA Comprehensive clinical and safety monograph for ISTURISA (ISTURISA). | Cortisol Synthesis Inhibitor | ISTURISA | caution |
ISUPREL Comprehensive clinical and safety monograph for ISUPREL (ISUPREL). | Beta-Adrenergic Agonist | ISUPREL | caution |
ITOVEBI Comprehensive clinical and safety monograph for ITOVEBI (ITOVEBI). | Fluoroquinolone Antibiotic | ITOVEBI | caution |
ITRACONAZOLE Inhibits CYP3A4 increasing levels of many drugs (eg statins) Contraindicated with drugs that prolong QT interval and can cause negative inotropy and heart failure. | Azole Antifungal | ITRACONAZOLE | avoid |
IV PERSANTINE Comprehensive clinical and safety monograph for IV PERSANTINE (IV PERSANTINE). | Vasodilator | IV PERSANTINE | caution |
IVABRADINE HYDROCHLORIDE Strong CYP3A4 inhibitors may increase levels Can cause bradycardia and phosphenes (visual brightness). | Hyperpolarization-Activated Cyclic Nucleotide–Gated (HCN) Channel Blocker | IVABRADINE HYDROCHLORIDE | safe |
IVACAFTOR Strong CYP3A4 inhibitors may increase levels Can cause elevated liver enzymes and non-congenital cataracts. | CFTR Potentiator | IVACAFTOR | safe |
IVADANTIN Comprehensive clinical and safety monograph for IVADANTIN (IVADANTIN). | Nitrofuran Antibiotic | IVADANTIN | caution |
IVERMECTIN No significant drug interactions Can cause Mazzotti reaction (inflammatory response) in patients with high parasitic load. | Anthelmintic | IVERMECTIN | safe |
IVRA Comprehensive clinical and safety monograph for IVRA (IVRA). | Nonsteroidal Anti-Inflammatory Drug (NSAID) | IVRA | caution |
IVY BLOCK Comprehensive clinical and safety monograph for IVY BLOCK (IVY BLOCK). | Barrier Cream | IVY BLOCK | caution |
IWILFIN Comprehensive clinical and safety monograph for IWILFIN (IWILFIN). | Mineralocorticoid Receptor Antagonist | IWILFIN | caution |
IXEMPRA KIT Comprehensive clinical and safety monograph for IXEMPRA KIT (IXEMPRA KIT). | Antineoplastic Microtubule Inhibitor | IXEMPRA KIT | caution |
IXIFI Comprehensive clinical and safety monograph for IXIFI (IXIFI). | Tumor Necrosis Factor (TNF) Inhibitor | IXIFI | caution |
IYUZEH Comprehensive clinical and safety monograph for IYUZEH (IYUZEH). | Wound Therapy | IYUZEH | caution |
IZBA Comprehensive clinical and safety monograph for IZBA (IZBA). | Angiotensin II Receptor Antagonist | IZBA | caution |
IZERVAY Comprehensive clinical and safety monograph for IZERVAY (IZERVAY). | Complement C5 Inhibitor | IZERVAY | caution |
JADELLE Comprehensive clinical and safety monograph for JADELLE (JADELLE). | Progestin Implant Contraceptive | JADELLE | caution |
JADENU Comprehensive clinical and safety monograph for JADENU (JADENU). | Iron Chelator | JADENU | caution |
JADENU SPRINKLE Comprehensive clinical and safety monograph for JADENU SPRINKLE (JADENU SPRINKLE). | Iron Chelator | JADENU SPRINKLE | caution |
JAIMIESS Comprehensive clinical and safety monograph for JAIMIESS (JAIMIESS). | Oral Contraceptive, Combined | JAIMIESS | caution |
JAKAFI Comprehensive clinical and safety monograph for JAKAFI (JAKAFI). | Janus Kinase Inhibitor | JAKAFI | caution |
JALYN Comprehensive clinical and safety monograph for JALYN (JALYN). | 5-Alpha Reductase Inhibitor/Alpha-1 Blocker Combination | JALYN | caution |
JANIMINE Comprehensive clinical and safety monograph for JANIMINE (JANIMINE). | Tricyclic Antidepressant | JANIMINE | caution |
JANTOVEN Comprehensive clinical and safety monograph for JANTOVEN (JANTOVEN). | Vitamin K Antagonist | JANTOVEN | caution |
JANUMET Comprehensive clinical and safety monograph for JANUMET (JANUMET). | DPP-4 Inhibitor/Biguanide Combination | JANUMET | caution |
JANUMET XR Comprehensive clinical and safety monograph for JANUMET XR (JANUMET XR). | DPP-4 Inhibitor/Biguanide Combination | JANUMET XR | caution |
JANUVIA Comprehensive clinical and safety monograph for JANUVIA (JANUVIA). | DPP-4 Inhibitor | JANUVIA | caution |
JARDIANCE Comprehensive clinical and safety monograph for JARDIANCE (JARDIANCE). | SGLT2 Inhibitor | JARDIANCE | caution |
JASCAYD Comprehensive clinical and safety monograph for JASCAYD (JASCAYD). | Tyrosine Kinase Inhibitor | JASCAYD | caution |
JATENZO Comprehensive clinical and safety monograph for JATENZO (JATENZO). | Androgen Replacement Therapy | JATENZO | caution |
JAVADIN Comprehensive clinical and safety monograph for JAVADIN (JAVADIN). | Antineoplastic Agent | JAVADIN | caution |
JAYPIRCA Comprehensive clinical and safety monograph for JAYPIRCA (JAYPIRCA). | Diagnostic Radiopharmaceutical | JAYPIRCA | caution |
JAYTHARI Comprehensive clinical and safety monograph for JAYTHARI (JAYTHARI). | Oral Contraceptive | JAYTHARI | caution |
JEANATOPE Comprehensive clinical and safety monograph for JEANATOPE (JEANATOPE). | Antihemophilic Factor | JEANATOPE | caution |
JELMYTO Comprehensive clinical and safety monograph for JELMYTO (JELMYTO). | Antineoplastic Antibiotic | JELMYTO | caution |
JEMPERLI Comprehensive clinical and safety monograph for JEMPERLI (JEMPERLI). | PD-1 Inhibitor | JEMPERLI | caution |
JENCYCLA Comprehensive clinical and safety monograph for JENCYCLA (JENCYCLA). | Oral Contraceptive | JENCYCLA | caution |
JENLOGA Comprehensive clinical and safety monograph for JENLOGA (JENLOGA). | Oral Contraceptive | JENLOGA | caution |