SIMVASTATIN

Clinical safety rating: avoid

Contraindicated (not allowed)

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Tablet 20 mg - Oral

Dosage form	TABLET
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

Strong CYP3A4 inhibitors (eg itraconazole) can significantly increase levels and risk of myopathy Can cause myopathy and rhabdomyolysis.

myalgia

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Clinical safety rating: avoid

Contraindicated (not allowed)

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Tablet 20 mg - Oral

Dosage form	TABLET
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

Strong CYP3A4 inhibitors (eg itraconazole) can significantly increase levels and risk of myopathy Can cause myopathy and rhabdomyolysis.