Ionosol MB and Dextrose 5% in plastic container
Clinical Indications
Electrolyte and fluid replacement in patients with moderate electrolyte deficits. Provides a balanced multi-electrolyte profile suitable for post-operative fluid replacement or resuscitation where maintenance of K⁺, Mg²⁺, and Ca²⁺ balance is required.
Dosing & Administration Rate
Dose individualized based on patient fluid and electrolyte status. Typical adult dose: 1,500–2,000 mL/24 hrs. Monitor serum electrolytes and fluid balance. Adjust rate in renal impairment.
Warnings & Precautions
Hypertonic solution — can cause hyperglycaemia in diabetic patients. Monitor for hyperkalaemia in oliguric patients. Not suitable as a primary resuscitation fluid in hypovolaemia due to K⁺ content.
Contraindications
Renal failure, hyperkalemia, hypermagnesemia. Caution in severe cardiac disease or edema.
Pharmacology & Safety Profile
Mechanism of Action
Provides water, electrolytes, and calories. Contains magnesium and potassium to treat intracellular deficits.
Adverse Reactions
Electrolyte overload (especially potassium/magnesium), fluid overload, localized phlebitis.
Compatibility Notes
Compatible with standard IV sets. Consult pharmacist before adding medications.
Electrolyte & Composition Profile
| Component | Amount / Concentration |
|---|---|
| Dextrose (Anhydrous) | 50 mg/mL (5%) |
| Sodium Chloride (Na⁺ 25 mEq/L) | 1.46 g/L |
| Potassium Chloride (K⁺ 20 mEq/L) | 1.49 g/L |
| Calcium Chloride (Ca²⁺ 3 mEq/L) | 0.22 g/L |
| Magnesium Chloride (Mg²⁺ 3 mEq/L) | 0.30 g/L |
| Sodium Acetate (Acetate 23 mEq/L) | 1.90 g/L |
| Sodium Gluconate (Gluconate 23 mEq/L) | 5.10 g/L |
| Water for Injection | q.s. |
| Caloric Density | 170 kcal/L (from dextrose) |
Clinical Parameters
Clinical Disclaimer: Data compiled from FDA DailyMed, Baxter/Fresenius prescribing information, and USP monographs. Always verify against the physical product label, your institution's IV protocols, and current pharmacist guidance before administration.
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