Forrest Classification: Endoscopic assessment of peptic ulcer bleeding. Predicts rebleeding risk and guides therapeutic intervention.
Guidelines & Evidence
Clinical Details
Section 1
When to Use
When to Use
Endoscopic assessment of peptic ulcers presenting with acute gastrointestinal bleeding
To guide the decision for endoscopic haemostasis (thermal, clips, or injectables)
To predict the risk of re-bleeding and associated mortality
To assist in triage decisions (ICU vs. ward monitored discharge)
Timing of Endoscopy
Clinical guidelines (ACG/ESGE) recommend performing endoscopy within 24 hours of presentation. In high-risk patients (haemodynamic instability), earlier endoscopy (< 12 hours) should be considered after resuscitation.
Grade IIa: Visible non-bleeding vessel (High risk for re-bleed).
04
Grade IIb: Adherent clot (Cannot be washed away; obscures vessel).
05
Grade IIc: Haematin-covered flat spot (Low risk).
06
Grade III: Clean based ulcer (Minimal risk).
Risk of Re-bleeding without Therapy
Forrest Ia/Ib
55–90% risk of recurrence
Forrest IIa
43–55% risk of recurrence
Forrest IIb
22–33% risk of recurrence
Forrest IIc/III
< 5% risk of recurrence
Section 3
Pearls/Pitfalls
Mandatory Endoscopic Therapy
All Forest Ia, Ib, and IIa ulcers REQUIRE endoscopic intervention (Dual-modality: e.g., Epinephrine injection + Clips or Thermal cautery). Therapeutic intervention for IIb (adherent clot) is debated but often performed after removing the clot to expose the underlying vessel.
Early Discharge Candidate
A Forrest III (clean base) ulcer in a clinically stable patient with a low Glasgow-Blatchford Score (< 2) is a candidate for early discharge and outpatient management.
Clinical Pearls
Forrest IIa (visible vessel) is the most "dangerous" subtle finding; it carries a massive re-bleed risk even if not actively bleeding at the moment of inspection
PPI "Bolus and Drip" (80mg + 8mg/hr) is indicated for Forrest Ia, Ib, IIa, and IIb to maximize stable clot formation
Re-inspection endoscopy is not routinely indicated unless clinical evidence of re-bleeding occurs
Section 4
Next Steps
Management Pathways
01
Class I - IIa: Admit (72-hour observation); IV PPI; Liquid to regular diet as tolerated after 24h stability.
02
Class IIc - III: Step-down care; Oral PPI; Early discharge consideration.
Complementary Scoring
Glasgow-Blatchford Score (Pre-endoscopy)
Rockall Score (Post-endoscopy)
AIMS65 Score (Mortality)
Section 5
Evidence Appraisal
Foundational Classification
Endoscopy in gastrointestinal bleeding.
Forrest JA et al. • Lancet. 1974;2(7877):394-7. The foundational paper establishing the nomenclature.
Developed by J.A. Forrest in 1974 at the Royal Infirmary of Edinburgh. It provided the first reproducible language for endoscopists to communicate the "activity" of an ulcer. Before this, terms like "bleeding ulcer" were generic and failed to predict which patients were actually at high risk of rapid exsanguination.