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Clinical Notice:OpiCalc is not a substitute for professional clinical judgment. Always verify dosages and guidelines.

OpiCalc © 2018-2026

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Registry Hub

Therapeutic Classification

estrogen Registry

Clinical reference for estrogen medications. Access safety monographs, dosing adjustments, and drug-drug interactions for all registered brand names and generics in this class.

Registered Medications (estrogen)

This therapeutic registry is dynamically synthesized from professional clinical sources. Listing of a medication does not imply equivalence; refer to individual monographs for head-to-head pharmacological data.

MedicationTherapeutic ClassMaternal Safety

ACTIVELLA

Comprehensive clinical and safety monograph for ACTIVELLA (ACTIVELLA).

Estrogen/Progestin Combination

caution

ALESSE

Comprehensive clinical and safety monograph for ALESSE (ALESSE).

Estrogen/Progestin Combination Contraceptive

caution

ALORA

Comprehensive clinical and safety monograph for ALORA (ALORA).

Estrogen

caution

AMNESTROGEN

Comprehensive clinical and safety monograph for AMNESTROGEN (AMNESTROGEN).

Estrogen

caution

AMOSENE

Comprehensive clinical and safety monograph for AMOSENE (AMOSENE).

Estrogen

caution

ANDROID-F

Comprehensive clinical and safety monograph for ANDROID-F (ANDROID-F).

Androgen/Estrogen Combination

caution

AYUNA

Comprehensive clinical and safety monograph for AYUNA (AYUNA).

Estrogen Receptor Agonist

caution

BIJUVA

Comprehensive clinical and safety monograph for BIJUVA (BIJUVA).

Hormone Therapy (Estrogen-Progestin)

caution

BREXAFEMME

Comprehensive clinical and safety monograph for BREXAFEMME (BREXAFEMME).

Estrogen

caution

CENESTIN

Comprehensive clinical and safety monograph for CENESTIN (CENESTIN).

Estrogen

caution

CHLOROTRIANISENE

Comprehensive clinical and safety monograph for CHLOROTRIANISENE (CHLOROTRIANISENE).

Estrogen

caution

CLIMARA

Comprehensive clinical and safety monograph for CLIMARA (CLIMARA).

Estrogen

caution

CLIMARA PRO

Comprehensive clinical and safety monograph for CLIMARA PRO (CLIMARA PRO).

Estrogen/Progestin Combination

caution

CLOMID

Comprehensive clinical and safety monograph for CLOMID (CLOMID).

Selective Estrogen Receptor Modulator

caution

CLOMIPHENE CITRATE

No significant drug interactions May cause visual disturbances and ovarian hyperstimulation syndrome.

Selective Estrogen Receptor Modulator (SERM)

safe

COMBIPATCH

Comprehensive clinical and safety monograph for COMBIPATCH (COMBIPATCH).

Hormone Replacement Therapy (Estrogen/Progestin)

caution

CONJUGATED ESTROGENS

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

CONJUPRI

Comprehensive clinical and safety monograph for CONJUPRI (CONJUPRI).

Estrogen Replacement

caution

DELESTROGEN

Comprehensive clinical and safety monograph for DELESTROGEN (DELESTROGEN).

Estrogen

caution

DEPO-ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

DESOGESTREL AND ETHINYL ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

DIENESTROL

Comprehensive clinical and safety monograph for DIENESTROL (DIENESTROL).

Estrogen

caution

DIETHYLSTILBESTROL

Comprehensive clinical and safety monograph for DIETHYLSTILBESTROL (DIETHYLSTILBESTROL).

Estrogen

caution

DIVIGEL

Comprehensive clinical and safety monograph for DIVIGEL (DIVIGEL).

Estrogen

caution

DROSPIRENONE AND ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

DROSPIRENONE AND ETHINYL ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

DROSPIRENONE, ETHINYL ESTRADIOL AND LEVOMEFOLATE CALCIUM

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Progestin + Estrogen

avoid

DUAVEE

Comprehensive clinical and safety monograph for DUAVEE (DUAVEE).

Selective Estrogen Receptor Modulator/Estrogen Combination

caution

DURAPREP

Comprehensive clinical and safety monograph for DURAPREP (DURAPREP).

Estrogen

caution

ELESTRIN

Comprehensive clinical and safety monograph for ELESTRIN (ELESTRIN).

Estrogen Replacement Therapy

caution

ENJUVIA

Comprehensive clinical and safety monograph for ENJUVIA (ENJUVIA).

Estrogen Replacement Therapy

caution

ESCLIM

Comprehensive clinical and safety monograph for ESCLIM (ESCLIM).

Estrogen

caution

ESTERIFIED ESTROGENS

Comprehensive clinical and safety monograph for ESTERIFIED ESTROGENS (ESTERIFIED ESTROGENS).

Estrogen

caution

ESTINYL

Comprehensive clinical and safety monograph for ESTINYL (ESTINYL).

Estrogen

caution

ESTRACE

Comprehensive clinical and safety monograph for ESTRACE (ESTRACE).

Estrogen

caution

ESTRADERM

Comprehensive clinical and safety monograph for ESTRADERM (ESTRADERM).

Estrogen

caution

ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

ESTRADIOL AND NORGESTIMATE

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

ESTRADIOL CYPIONATE

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

ESTRADIOL VALERATE

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

ESTRADIOL VALERATE AND DIENOGEST

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

ESTRADIOL VALERATE; ESTRADIOL VALERATE; DIENOGEST

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

ESTRADURIN

Comprehensive clinical and safety monograph for ESTRADURIN (ESTRADURIN).

Estrogen

caution

ESTRAGUARD

Comprehensive clinical and safety monograph for ESTRAGUARD (ESTRAGUARD).

Estrogen

caution

ESTRASORB

Comprehensive clinical and safety monograph for ESTRASORB (ESTRASORB).

Estrogen

caution

ESTRATAB

Comprehensive clinical and safety monograph for ESTRATAB (ESTRATAB).

Estrogen

caution

ESTRING

Comprehensive clinical and safety monograph for ESTRING (ESTRING).

Estrogen

caution

ESTROGEL

Comprehensive clinical and safety monograph for ESTROGEL (ESTROGEL).

Estrogen

caution

ESTROGENIC SUBSTANCE

Comprehensive clinical and safety monograph for ESTROGENIC SUBSTANCE (ESTROGENIC SUBSTANCE).

Estrogen

caution

ESTRONE

Comprehensive clinical and safety monograph for ESTRONE (ESTRONE).

Estrogen

caution

ESTROPIPATE

Comprehensive clinical and safety monograph for ESTROPIPATE (ESTROPIPATE).

Estrogen

caution

ESTROVIS

Comprehensive clinical and safety monograph for ESTROVIS (ESTROVIS).

Estrogen

caution

ETHINYL ESTRADIOL AND LEVONORGESTREL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

ETHINYL ESTRADIOL AND NORELGESTROMIN

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

ETHINYL ESTRADIOL; LEVONORGESTREL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

ETHYNODIOL DIACETATE AND ETHINYL ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

EVAMIST

Comprehensive clinical and safety monograph for EVAMIST (EVAMIST).

Estrogen Replacement

caution

EVEX

Comprehensive clinical and safety monograph for EVEX (EVEX).

Estrogen

caution

EVISTA

Comprehensive clinical and safety monograph for EVISTA (EVISTA).

Selective Estrogen Receptor Modulator

caution

FARESTON

Comprehensive clinical and safety monograph for FARESTON (FARESTON).

Selective Estrogen Receptor Modulator

caution

FASLODEX

Comprehensive clinical and safety monograph for FASLODEX (FASLODEX).

Estrogen Receptor Antagonist

caution

FEMINONE

Comprehensive clinical and safety monograph for FEMINONE (FEMINONE).

Estrogen

caution

FEMOGEN

Comprehensive clinical and safety monograph for FEMOGEN (FEMOGEN).

Estrogen

caution

FEMPATCH

Comprehensive clinical and safety monograph for FEMPATCH (FEMPATCH).

Estrogen Transdermal

caution

FEMRING

Comprehensive clinical and safety monograph for FEMRING (FEMRING).

Estrogen

caution

FEMTRACE

Comprehensive clinical and safety monograph for FEMTRACE (FEMTRACE).

Estrogen

caution

FULVESTRANT

No significant drug interactions Can cause injection site reactions and nausea.

Estrogen Receptor Antagonist

avoid

GYNODIOL

Comprehensive clinical and safety monograph for GYNODIOL (GYNODIOL).

Estrogen

caution

IMVEXXY

Comprehensive clinical and safety monograph for IMVEXXY (IMVEXXY).

Estrogen

caution

INTRAROSA

Comprehensive clinical and safety monograph for INTRAROSA (INTRAROSA).

Estrogen

caution

KEMSTRO

Comprehensive clinical and safety monograph for KEMSTRO (KEMSTRO).

Estrogen Hormone Replacement Therapy

caution

KLAYESTA

Comprehensive clinical and safety monograph for KLAYESTA (KLAYESTA).

Vaginal Estrogen

caution

KYRA

Comprehensive clinical and safety monograph for KYRA (KYRA).

Estrogen Agonist/Antagonist

caution

LEVONORGESTREL AND ETHINYL ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

LEVONORGESTREL AND ETHINYL ESTRADIOL AND ETHINYL ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

LEVONORGESTREL AND ETHINYL ESTRADIOL AND FERROUS FUMARATE

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

LYGEN

Comprehensive clinical and safety monograph for LYGEN (LYGEN).

Estrogen

caution

MENEST

Comprehensive clinical and safety monograph for MENEST (MENEST).

Estrogen Replacement Therapy

caution

MENOSTAR

Comprehensive clinical and safety monograph for MENOSTAR (MENOSTAR).

Estrogen Replacement Therapy

caution

MENRIUM 10-4

Comprehensive clinical and safety monograph for MENRIUM 10-4 (MENRIUM 10-4).

Benzodiazepine/Estrogen Combination

caution

MENRIUM 5-2

Comprehensive clinical and safety monograph for MENRIUM 5-2 (MENRIUM 5-2).

Benzodiazepine/Estrogen Combination

caution

MENRIUM 5-4

Comprehensive clinical and safety monograph for MENRIUM 5-4 (MENRIUM 5-4).

Benzodiazepine/Estrogen Combination

caution

MILOPHENE

Comprehensive clinical and safety monograph for MILOPHENE (MILOPHENE).

Selective Estrogen Receptor Modulator

caution

MINIVELLE

Comprehensive clinical and safety monograph for MINIVELLE (MINIVELLE).

Estrogen Replacement

caution

NATURAL ESTROGENIC SUBSTANCE-ESTRONE

Comprehensive clinical and safety monograph for NATURAL ESTROGENIC SUBSTANCE-ESTRONE (NATURAL ESTROGENIC SUBSTANCE-ESTRONE).

Estrogen

caution

NOLVADEX

Comprehensive clinical and safety monograph for NOLVADEX (NOLVADEX).

Selective Estrogen Receptor Modulator

caution

NORGESTIMATE AND ETHINYL ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

NORGESTIMATE; ETHINYL ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Progestin + Estrogen

avoid

NORGESTREL AND ETHINYL ESTRADIOL

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

NUTRESTORE

Comprehensive clinical and safety monograph for NUTRESTORE (NUTRESTORE).

Estrogen

caution

NUVESSA

Comprehensive clinical and safety monograph for NUVESSA (NUVESSA).

Estrogen

caution

OGEN

Comprehensive clinical and safety monograph for OGEN (OGEN).

Estrogen

caution

OGEN .625

Comprehensive clinical and safety monograph for OGEN .625 (OGEN .625).

Estrogen

caution

OGEN 1.25

Comprehensive clinical and safety monograph for OGEN 1.25 (OGEN 1.25).

Estrogen

caution

OGEN 2.5

Comprehensive clinical and safety monograph for OGEN 2.5 (OGEN 2.5).

Estrogen

caution

OGEN 5

Comprehensive clinical and safety monograph for OGEN 5 (OGEN 5).

Estrogen

caution

ONEXTON

Comprehensive clinical and safety monograph for ONEXTON (ONEXTON).

Hormonal Contraceptive (Estrogen-Progestin Combination)

caution

ORSERDU

Comprehensive clinical and safety monograph for ORSERDU (ORSERDU).

Estrogen receptor antagonist

caution

ORTHO-EST

Comprehensive clinical and safety monograph for ORTHO-EST (ORTHO-EST).

Estrogen Replacement

caution

OSPEMIFENE

Comprehensive clinical and safety monograph for OSPEMIFENE (OSPEMIFENE).

Selective Estrogen Receptor Modulator (SERM)

caution

OSPHENA

Comprehensive clinical and safety monograph for OSPHENA (OSPHENA).

Selective Estrogen Receptor Modulator (SERM)

caution

PMB 200

Comprehensive clinical and safety monograph for PMB 200 (PMB 200).

Estrogen/Progestin Combination

caution

PMB 400

Comprehensive clinical and safety monograph for PMB 400 (PMB 400).

Estrogen/Progestin Combination

caution

PREFEST

Comprehensive clinical and safety monograph for PREFEST (PREFEST).

Estrogen/Progestin Combination Hormone Therapy

caution

PRELAY

Comprehensive clinical and safety monograph for PRELAY (PRELAY).

Estrogen Hormone Therapy

caution

PREMARIN

Comprehensive clinical and safety monograph for PREMARIN (PREMARIN).

Estrogen Hormone Therapy

caution

PREMPHASE (PREMARIN;CYCRIN 14/14)

Comprehensive clinical and safety monograph for PREMPHASE (PREMARIN;CYCRIN 14/14) (PREMPHASE (PREMARIN;CYCRIN 14/14)).

Estrogen/Progestin Combination

caution

PREMPHASE 14/14

Comprehensive clinical and safety monograph for PREMPHASE 14/14 (PREMPHASE 14/14).

Estrogen/Progestin Combination

caution

PREMPRO

Comprehensive clinical and safety monograph for PREMPRO (PREMPRO).

Estrogen/Progestin Combination

caution

PREMPRO (PREMARIN;CYCRIN)

Comprehensive clinical and safety monograph for PREMPRO (PREMARIN;CYCRIN) (PREMPRO (PREMARIN;CYCRIN)).

Estrogen/Progestin Combination

caution

PREMPRO/PREMPHASE

Comprehensive clinical and safety monograph for PREMPRO/PREMPHASE (PREMPRO/PREMPHASE).

Estrogen/Progestin Combination

caution

SAFYRAL

Comprehensive clinical and safety monograph for SAFYRAL (SAFYRAL).

Oral Contraceptive Progestin/Estrogen

caution

SOLTAMOX

Comprehensive clinical and safety monograph for SOLTAMOX (SOLTAMOX).

Selective Estrogen Receptor Modulator

caution

STILBESTROL

Comprehensive clinical and safety monograph for STILBESTROL (STILBESTROL).

Estrogen

caution

STILBETIN

Comprehensive clinical and safety monograph for STILBETIN (STILBETIN).

Estrogen

caution

STILPHOSTROL

Comprehensive clinical and safety monograph for STILPHOSTROL (STILPHOSTROL).

Estrogen

caution

SYNTHETIC CONJUGATED ESTROGENS A

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Estrogen

avoid

TACE

Comprehensive clinical and safety monograph for TACE (TACE).

Estrogen

caution

THEELIN

Comprehensive clinical and safety monograph for THEELIN (THEELIN).

Estrogen

caution

TOREMIFENE CITRATE

Comprehensive clinical and safety monograph for TOREMIFENE CITRATE (TOREMIFENE CITRATE).

Selective Estrogen Receptor Modulator

caution

TRIVORA-21

Comprehensive clinical and safety monograph for TRIVORA-21 (TRIVORA-21).

Oral Contraceptive (Estrogen/Progestin Combination)

caution

TRIVORA-28

Comprehensive clinical and safety monograph for TRIVORA-28 (TRIVORA-28).

Oral Contraceptive (Estrogen/Progestin Combination)

caution

VAGIFEM

Comprehensive clinical and safety monograph for VAGIFEM (VAGIFEM).

Estrogen

caution

VENXXIVA

Comprehensive clinical and safety monograph for VENXXIVA (VENXXIVA).

Estrogen (Vaginal)

caution

VIVELLE

Comprehensive clinical and safety monograph for VIVELLE (VIVELLE).

Estrogen Replacement

caution

VIVELLE-DOT

Comprehensive clinical and safety monograph for VIVELLE-DOT (VIVELLE-DOT).

Estrogen Replacement

caution