DROSPIRENONE AND ESTRADIOL

Clinical safety rating: avoid

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

How it works

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Tablet 1 mg - Oral

Dosage form	TABLET
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

FDA category

Category Positive

Breast tenderness

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Clinical safety rating: avoid

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

Mechanism information is still being processed. Check the DailyMed link in the sidebar for the official prescribing information.

Tablet 1 mg - Oral

Dosage form	TABLET
Renal impairment	Consult protocols for adjustment.
Liver impairment	Consult protocols for adjustment.

Clinical note

Inducers of CYP450 enzymes (eg carbamazepine) may decrease estrogen levels Increases risk of thromboembolic disorders and endometrial cancer.

FDA category

Category Positive

Breast tenderness

Loading safety data…