Oseltamivir
Recommended for treatment of influenza in pregnancy regardless of trimester. Pregnant women are at high risk for severe influenza (pneumonia, preterm birth, maternal death). Benefits clearly outweigh risks. Treatment should be initiated within 48 hours of symptom onset. Prophylaxis is also appropriate after significant exposure. No evidence of teratogenicity. Influenza vaccination during pregnancy is separately recommended by ACOG/CDC.