PHRENILIN WITH CAFFEINE AND CODEINE CNS depressants including alcohol and benzodiazepines increase sedation risk Life-threatening respiratory depression may occur especially in CYP2D6 ultra-rapid metabolizers. | Opioid Agonist | PHRENILIN WITH CAFFEINE AND CODEINE | avoid |
PHYLLOCONTIN Comprehensive clinical and safety monograph for PHYLLOCONTIN (PHYLLOCONTIN). | Xanthine Bronchodilator | PHYLLOCONTIN | caution |
PHYRAGO Comprehensive clinical and safety monograph for PHYRAGO (PHYRAGO). | Antihistamine | PHYRAGO | caution |
PHYSIOLYTE IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PHYSIOLYTE IN PLASTIC CONTAINER (PHYSIOLYTE IN PLASTIC CONTAINER). | Irrigation Solution | PHYSIOLYTE IN PLASTIC CONTAINER | caution |
PHYSIOSOL IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PHYSIOSOL IN PLASTIC CONTAINER (PHYSIOSOL IN PLASTIC CONTAINER). | Irrigation Solution | PHYSIOSOL IN PLASTIC CONTAINER | caution |
PHYSIOSOL PH 7.4 IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PHYSIOSOL PH 7.4 IN PLASTIC CONTAINER (PHYSIOSOL PH 7.4 IN PLASTIC CONTAINER). | Irrigation Solution | PHYSIOSOL PH 7.4 IN PLASTIC CONTAINER | caution |
PHYTONADIONE Comprehensive clinical and safety monograph for PHYTONADIONE (PHYTONADIONE). | Vitamin K (Coagulation Factor) | PHYTONADIONE | caution |
PIASKY Comprehensive clinical and safety monograph for PIASKY (PIASKY). | Sphingosine 1-Phosphate Receptor Modulator | PIASKY | caution |
PICATO Comprehensive clinical and safety monograph for PICATO (PICATO). | Topical Antineoplastic | PICATO | caution |
PIFELTRO Comprehensive clinical and safety monograph for PIFELTRO (PIFELTRO). | NNRTI | PIFELTRO | caution |
PILOPINE HS Comprehensive clinical and safety monograph for PILOPINE HS (PILOPINE HS). | Miotic | PILOPINE HS | caution |
PIMAVANSERIN Strong CYP3A4 inhibitors may increase levels and inducers may decrease levels Can prolong the QT interval. | Serotonin Inverse Agonist | PIMAVANSERIN | safe |
PIMECROLIMUS No significant drug interactions May increase risk of skin malignancies and lymphomas. | Calcineurin Inhibitor | PIMECROLIMUS | safe |
PIMOZIDE Strong CYP3A4 inhibitors are contraindicated due to risk of QT prolongation Can cause QT prolongation and extrapyramidal symptoms. | Typical Antipsychotic | PIMOZIDE | safe |
PIMTREA Comprehensive clinical and safety monograph for PIMTREA (PIMTREA). | Oral Contraceptive | PIMTREA | caution |
PINDAC Comprehensive clinical and safety monograph for PINDAC (PINDAC). | Beta Blocker | PINDAC | caution |
PINDOLOL Other drugs that lower heart rate or blood pressure can have additive effects Abrupt withdrawal may exacerbate angina pectoris or cause myocardial infarction. | Beta-Blocker | PINDOLOL | safe |
PIOGLITAZONE Strong CYP2C8 inhibitors may increase levels Can cause or exacerbate congestive heart failure and bladder cancer. | Thiazolidinedione | PIOGLITAZONE | safe |
PIOGLITAZONE HYDROCHLORIDE AND GLIMEPIRIDE Strong CYP2C8 inhibitors may increase levels Can cause or exacerbate congestive heart failure and bladder cancer. | Thiazolidinedione | PIOGLITAZONE HYDROCHLORIDE AND GLIMEPIRIDE | safe |
PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE Strong CYP2C8 inhibitors may increase levels Can cause or exacerbate congestive heart failure and bladder cancer. | Thiazolidinedione | PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE | safe |
PIPERACILLIN Comprehensive clinical and safety monograph for PIPERACILLIN (PIPERACILLIN). | Penicillin Antibiotic | PIPERACILLIN | caution |
PIPERACILLIN AND TAZOBACTAM Comprehensive clinical and safety monograph for PIPERACILLIN AND TAZOBACTAM (PIPERACILLIN AND TAZOBACTAM). | Penicillin Antibiotic / Beta-Lactamase Inhibitor Combination | PIPERACILLIN AND TAZOBACTAM | caution |
PIPERACILLIN AND TAZOBACTAM AND SODIUM CHLORIDE IN DUPLEX CONTAINER No significant drug interactions Can cause hypernatremia and fluid overload. | Electrolyte | PIPERACILLIN AND TAZOBACTAM AND SODIUM CHLORIDE IN DUPLEX CONTAINER | safe |
Piperacillin-Tazobactam Broad-spectrum beta-lactam/beta-lactamase inhibitor combination used IV for polymicrobial serious infections in pregnancy including chorioamnionitis, complicated UTI/pyelonephritis, and postpartum endometritis. No evidence of teratogenicity. Commonly used in obstetric practice for serious infections requiring broad coverage. | Penicillin Antibiotic + Beta-Lactamase Inhibitor | | safe |
PIPERAZINE CITRATE Comprehensive clinical and safety monograph for PIPERAZINE CITRATE (PIPERAZINE CITRATE). | Anthelmintic | PIPERAZINE CITRATE | caution |
PIPRACIL Comprehensive clinical and safety monograph for PIPRACIL (PIPRACIL). | Penicillin Antibiotic | PIPRACIL | caution |
PIQRAY Comprehensive clinical and safety monograph for PIQRAY (PIQRAY). | PI3K Inhibitor | PIQRAY | caution |
PIRFENIDONE Comprehensive clinical and safety monograph for PIRFENIDONE (PIRFENIDONE). | Antifibrotic Agent | PIRFENIDONE | caution |
PIRMELLA 1/35 Comprehensive clinical and safety monograph for PIRMELLA 1/35 (PIRMELLA 1/35). | Oral Contraceptive | PIRMELLA 1/35 | caution |
PIRMELLA 7/7/7 Comprehensive clinical and safety monograph for PIRMELLA 7/7/7 (PIRMELLA 7/7/7). | Oral Contraceptive | PIRMELLA 7/7/7 | caution |
PIROXICAM ACE inhibitors and ARBs may have diminished antihypertensive effect Increases risk of serious cardiovascular thrombotic events and GI bleeding. | NSAID | PIROXICAM | avoid |
PITAVASTATIN CALCIUM Cyclosporine may increase levels Can cause myopathy and rhabdomyolysis. | Statin | PITAVASTATIN CALCIUM | avoid |
PITOCIN Comprehensive clinical and safety monograph for PITOCIN (PITOCIN). | Oxytocic | PITOCIN | caution |
PITOLISANT Comprehensive clinical and safety monograph for PITOLISANT (PITOLISANT). | Histamine H3 Receptor Antagonist | PITOLISANT | caution |
PITRESSIN TANNATE Comprehensive clinical and safety monograph for PITRESSIN TANNATE (PITRESSIN TANNATE). | Antidiuretic Hormone Analog | PITRESSIN TANNATE | caution |
PIVYA Comprehensive clinical and safety monograph for PIVYA (PIVYA). | Opioid Partial Agonist | PIVYA | caution |
PIZENSY Comprehensive clinical and safety monograph for PIZENSY (PIZENSY). | Probiotic | PIZENSY | caution |
PLACIDYL Comprehensive clinical and safety monograph for PLACIDYL (PLACIDYL). | Sedative-Hypnotic | PLACIDYL | caution |
PLAN B Comprehensive clinical and safety monograph for PLAN B (PLAN B). | Emergency Contraceptive | PLAN B | caution |
PLAN B ONE-STEP Comprehensive clinical and safety monograph for PLAN B ONE-STEP (PLAN B ONE-STEP). | Emergency Contraceptive | PLAN B ONE-STEP | caution |
PLAQUENIL Comprehensive clinical and safety monograph for PLAQUENIL (PLAQUENIL). | Antimalarial | PLAQUENIL | caution |
PLASMA-LYTE 148 AND DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PLASMA-LYTE 148 AND DEXTROSE 5% IN PLASTIC CONTAINER (PLASMA-LYTE 148 AND DEXTROSE 5% IN PLASTIC CONTAINER). | Intravenous Electrolyte Solution | PLASMA-LYTE 148 AND DEXTROSE 5% IN PLASTIC CONTAINER | caution |
PLASMA-LYTE 148 IN WATER IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PLASMA-LYTE 148 IN WATER IN PLASTIC CONTAINER (PLASMA-LYTE 148 IN WATER IN PLASTIC CONTAINER). | Intravenous Electrolyte Solution | PLASMA-LYTE 148 IN WATER IN PLASTIC CONTAINER | caution |
PLASMA-LYTE 56 AND DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PLASMA-LYTE 56 AND DEXTROSE 5% IN PLASTIC CONTAINER (PLASMA-LYTE 56 AND DEXTROSE 5% IN PLASTIC CONTAINER). | Intravenous Electrolyte Solution | PLASMA-LYTE 56 AND DEXTROSE 5% IN PLASTIC CONTAINER | caution |
PLASMA-LYTE 56 IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PLASMA-LYTE 56 IN PLASTIC CONTAINER (PLASMA-LYTE 56 IN PLASTIC CONTAINER). | Intravenous Electrolyte Solution | PLASMA-LYTE 56 IN PLASTIC CONTAINER | caution |
PLASMA-LYTE A IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PLASMA-LYTE A IN PLASTIC CONTAINER (PLASMA-LYTE A IN PLASTIC CONTAINER). | Intravenous Electrolyte Solution | PLASMA-LYTE A IN PLASTIC CONTAINER | caution |
PLASMA-LYTE M AND DEXTROSE 5% IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PLASMA-LYTE M AND DEXTROSE 5% IN PLASTIC CONTAINER (PLASMA-LYTE M AND DEXTROSE 5% IN PLASTIC CONTAINER). | Intravenous Electrolyte Solution | PLASMA-LYTE M AND DEXTROSE 5% IN PLASTIC CONTAINER | caution |
PLASMA-LYTE R IN PLASTIC CONTAINER Comprehensive clinical and safety monograph for PLASMA-LYTE R IN PLASTIC CONTAINER (PLASMA-LYTE R IN PLASTIC CONTAINER). | Intravenous Electrolyte Solution | PLASMA-LYTE R IN PLASTIC CONTAINER | caution |
PLATINOL Comprehensive clinical and safety monograph for PLATINOL (PLATINOL). | Platinum-based Chemotherapy | PLATINOL | caution |
PLATINOL-AQ Comprehensive clinical and safety monograph for PLATINOL-AQ (PLATINOL-AQ). | Platinum-based Chemotherapy | PLATINOL-AQ | caution |
