Progesterone (Vaginal)
Vaginal progesterone (200 mg suppository or 90 mg gel) is indicated for prevention of preterm birth in women with singleton pregnancies, no prior preterm birth, and a short cervix (≤25 mm) on transvaginal ultrasound at 16–24 weeks. Also used for luteal phase support in ART pregnancies. The FIGO guideline supports universal cervical length screening and vaginal progesterone treatment. Oral and IM progesterone have different indications and evidence bases.
