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DIFLUCAN IN SODIUM CHLORIDE 0.9%

No significant drug interactions Can cause hypernatremia and fluid overload.

DIFLUCAN IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER

No significant drug interactions Can cause hypernatremia and fluid overload.

DIFLUNISAL

Comprehensive clinical and safety monograph for DIFLUNISAL (DIFLUNISAL).

DIFLUPREDNATE

Comprehensive clinical and safety monograph for DIFLUPREDNATE (DIFLUPREDNATE).

DIGOXIN PEDIATRIC

Many drugs can increase levels (eg amiodarone verapamil) causing toxicity Can cause life-threatening arrhythmias due to its narrow therapeutic index.

DIHYDROERGOTAMINE MESYLATE

Strong CYP3A4 inhibitors (eg clarithromycin) are contraindicated due to risk of ergotism Contraindicated in coronary artery disease and uncontrolled hypertension.

DILACOR XR

Comprehensive clinical and safety monograph for DILACOR XR (DILACOR XR).

DILANTIN

Comprehensive clinical and safety monograph for DILANTIN (DILANTIN).

DILANTIN-125

Comprehensive clinical and safety monograph for DILANTIN-125 (DILANTIN-125).

DILANTIN-30

Comprehensive clinical and safety monograph for DILANTIN-30 (DILANTIN-30).

DILATRATE-SR

Comprehensive clinical and safety monograph for DILATRATE-SR (DILATRATE-SR).

DILAUDID

Comprehensive clinical and safety monograph for DILAUDID (DILAUDID).

DILAUDID-HP

Comprehensive clinical and safety monograph for DILAUDID-HP (DILAUDID-HP).

DILOR

Comprehensive clinical and safety monograph for DILOR (DILOR).

DILOR-400

Comprehensive clinical and safety monograph for DILOR-400 (DILOR-400).

DILT-CD

Comprehensive clinical and safety monograph for DILT-CD (DILT-CD).

DILTIAZEM HYDROCHLORIDE

CYP3A4 inhibitors can increase levels and inducers can decrease levels Can cause bradycardia and heart failure.

DILTIAZEM HYDROCHLORIDE IN 0.72% SODIUM CHLORIDE

No significant drug interactions Can cause hypernatremia and fluid overload.

DILTIAZEM HYDROCHLORIDE IN DEXTROSE 5%

CYP3A4 inhibitors can increase levels and inducers can decrease levels Can cause bradycardia and heart failure.

DILTZAC

Comprehensive clinical and safety monograph for DILTZAC (DILTZAC).

DIMENHYDRINATE

Comprehensive clinical and safety monograph for DIMENHYDRINATE (DIMENHYDRINATE).

DIMETANE

Comprehensive clinical and safety monograph for DIMETANE (DIMETANE).

DIMETANE-DX

Comprehensive clinical and safety monograph for DIMETANE-DX (DIMETANE-DX).

DIMETANE-TEN

Comprehensive clinical and safety monograph for DIMETANE-TEN (DIMETANE-TEN).

DIMETHYL FUMARATE

No significant drug interactions Can cause flushing and GI events (nausea diarrhea abdominal pain) usually at treatment initiation.

DIMETHYL SULFOXIDE

Comprehensive clinical and safety monograph for DIMETHYL SULFOXIDE (DIMETHYL SULFOXIDE).

Dinoprostone

Prostaglandin E2 used for cervical ripening prior to labor induction (intracervical gel or vaginal insert/Cervidil). Effective and safe for this indication in the third trimester. Must not be used in women with prior uterine surgery (classical cesarean scar) due to uterine rupture risk. Remove vaginal insert before initiating oxytocin. Prostaglandins are contraindicated as tocolytics (opposite mechanism).

DIONOSIL AQUEOUS

Comprehensive clinical and safety monograph for DIONOSIL AQUEOUS (DIONOSIL AQUEOUS).

DIONOSIL OILY

Comprehensive clinical and safety monograph for DIONOSIL OILY (DIONOSIL OILY).

DIOVAN

Comprehensive clinical and safety monograph for DIOVAN (DIOVAN).

DIOVAN HCT

Comprehensive clinical and safety monograph for DIOVAN HCT (DIOVAN HCT).

DIPENTUM

Comprehensive clinical and safety monograph for DIPENTUM (DIPENTUM).

DIPHEN

Comprehensive clinical and safety monograph for DIPHEN (DIPHEN).

Diphenhydramine

First-generation sedating antihistamine used for allergic conditions, sleep, and NVP. More sedating than second-generation agents. No established teratogenicity in humans but limited near-term use recommended. When used very close to delivery, associated with neonatal CNS depression, jitteriness, and respiratory issues. Prefer second-generation antihistamines (cetirizine, loratadine) for routine use.

DIPHENHYDRAMINE HYDROCHLORIDE

CNS depressants may enhance sedative effects May cause marked drowsiness and impair mental and physical abilities.

DIPHENHYDRAMINE HYDROCHLORIDE PRESERVATIVE FREE

CNS depressants may enhance sedative effects May cause marked drowsiness and impair mental and physical abilities.

DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE

Comprehensive clinical and safety monograph for DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE).

DIPHENOXYLATE HYDROCHLORIDE W/ ATROPINE SULFATE

Comprehensive clinical and safety monograph for DIPHENOXYLATE HYDROCHLORIDE W/ ATROPINE SULFATE (DIPHENOXYLATE HYDROCHLORIDE W/ ATROPINE SULFATE).

DIPHENYLAN SODIUM

Comprehensive clinical and safety monograph for DIPHENYLAN SODIUM (DIPHENYLAN SODIUM).

DIPIVEFRIN HYDROCHLORIDE

Comprehensive clinical and safety monograph for DIPIVEFRIN HYDROCHLORIDE (DIPIVEFRIN HYDROCHLORIDE).

DIPRIVAN

Comprehensive clinical and safety monograph for DIPRIVAN (DIPRIVAN).

DIPROLENE

Comprehensive clinical and safety monograph for DIPROLENE (DIPROLENE).

DIPROLENE AF

Comprehensive clinical and safety monograph for DIPROLENE AF (DIPROLENE AF).

DIPROSONE

Comprehensive clinical and safety monograph for DIPROSONE (DIPROSONE).

DIPYRIDAMOLE

Theophylline may antagonize the antiplatelet effect Can cause angina pectoris and hypotension in patients with coronary artery disease.

DIROXIMEL FUMARATE

Comprehensive clinical and safety monograph for DIROXIMEL FUMARATE (DIROXIMEL FUMARATE).

DISIPAL

Comprehensive clinical and safety monograph for DISIPAL (DISIPAL).

DISOBROM

Comprehensive clinical and safety monograph for DISOBROM (DISOBROM).

DISOMER

Comprehensive clinical and safety monograph for DISOMER (DISOMER).

DISOPHROL

Comprehensive clinical and safety monograph for DISOPHROL (DISOPHROL).