Acute Coronary Syndrome — USA (General Adult population)
After ACS hospitalization
Schedule early follow-up visit to reassess lipid levels and adjust lipid-lowering therapy to achieve LDL-C targets.
If patient experiences adverse effects from statin
Consider rechallenge at each visit or switch to a different statin or class of lipid-lowering therapy. Statin intolerance requires exposure to at least 2 different statins with 1 at lowest available dose.
If LDL-C is very low
Do not downtitrate lipid-lowering therapy; very low LDL-C is associated with lowest risk of MACE without safety concern.
Before prescribing new lipid-lowering therapy
Verify and discuss out-of-pocket costs with patient.
At follow-up visits
Educate patient about importance of lipid-lowering therapies and address barriers to adherence.
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