Diphtheria — Uganda (General Adult population)
Clinical Features
Pseudomembranous tonsillitis (grey, tough, sticky membranes) with dysphagia and cervical adenitis. May progress to massive neck swelling ("bull neck"). Airway obstruction when infection extends to nasal passages, larynx, trachea, bronchi. Low-grade fever. Toxin effects: cardiac dysfunction (myocarditis, heart failure), neuropathies (swallowing, vision, breathing, ambulation) 1–3 months after onset. Renal failure.
Investigations
Culture of throat/nasopharyngeal swab for Corynebacterium diphtheriae. Toxin detection.
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