Peptic Ulcer Disease — Uganda (General Adult population)
Symptomatic Relief
Modify diet. Magnesium trisilicate compound 2 tablets every 8 hours as required.
H. pylori Eradication (First Line Triple Therapy)
Amoxycillin 1 g every 12 hours PLUS Metronidazole 400 mg every 12 hours PLUS Omeprazole 20 mg every 12 hours for two weeks. (Tinidazole 500 mg 12-hourly can be used instead of metronidazole). Check eradication with stool antigen test after 4 weeks.
Bleeding and Perforated Ulcer
Refer patient immediately. Give IV fluids and blood if necessary. IV Ranitidine 50 mg in 20 ml slowly every 8 hours.
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