Peptic Ulcer Disease — Uganda (General Adult population)
Clinical Features
Duodenal ulcer: Epigastric pain typically worse at night and when hungry, alleviated by food/milk/antacids. Gastric ulcer: Epigastric pain worse with food. Vomiting, nausea, regurgitation.
Complications (Bleeding/Perforated)
Bleeding: Haematemesis, melena, sudden weakness, cold clammy skin. Perforated: Acute abdominal pain, rigid abdomen, shock.
Investigations
Positive stool antigen for H. pylori (false negatives if taking antibiotics or omeprazole in past 2 weeks). SERUM ANTIBODY TEST IS NOT USEFUL. Gastroscopy, biopsy, barium meal.
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