Syphilis — Uganda (General Adult population)
Primary, secondary, and early latent syphilis
Benzathine penicillin 2.4 million IU IM stat (half in each buttock). OR Doxycycline 100 mg every 12 hours for 14 days.
Late latent or tertiary (without neurosyphilis)
Benzathine penicillin 2.4 million IU IM weekly for 3 weeks. OR Doxycycline 100 mg every 12 hours for 28 days.
Neurosyphilis
Benzylpenicillin 4 million IU IV every 4 hours OR Ceftriaxone 2 g IV/IM daily for 10-14 days. Followed by Benzathine penicillin 2.4 million IU IM weekly for 3 weeks.
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