Uganda guidelines for the treatment of TB/HIV Co-Infection
Uganda Clinical Guidelines 2023 · all from source →
General Adult
Treatment
ART Initiation Timing
TB patients diagnosed with HIV: Start anti-TB medicines immediately, THEN start ARVs 2 weeks later. Adult TB patients diagnosed with TB: Start anti-TB medicines immediately, start ARVs before completing 2 weeks.
Patient already on ART, diagnosed with TB
Start anti-TB medicines immediately, adjust ARV regimen. If on EFV-based: Continue same regimen but double dose of DTG (give DTG twice daily). If on NVP-based: Substitute NVP with EFV, or use DTG twice daily, or triple NRTI (ABC+3TC+AZT). If on LPV/r: Continue and double DTG dose. If on ATV/r: Continue and give Rifabutin for TB treatment.
ARV Regimen in ART-naive patients on TB treatment
Adults/Adolescents/Pregnant: TDF+3TC+EFV. Children 3 to <12 years: ABC+3TC+EFV. Children 0 to <3 years: ABC+3TC+AZT.
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