Tuberculosis — Uganda (General Adult population)
Laboratory Monitoring (Pulmonary TB)
End of 2 months: If smear-negative, start continuation. If smear-positive, do GeneXpert to rule out Rifampicin resistance. Month 5: If smear-positive, diagnose Treatment Failure, do GeneXpert/culture, refer if DR-TB. Month 6: If smear-negative, complete treatment (Cured). If smear-positive, diagnose Treatment Failure.
Treatment Outcomes
Cure: Smear-negative in last month AND on at least one previous occasion. Treatment completed: Completed treatment without evidence of failure but missing final smear. Treatment failure: Positive smear at month 5 or later.
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