United States guidelines for the treatment of Type 2 Diabetes Mellitus

For patients of all ages with diabetes and ASCVD

Add high-intensity statin therapy to lifestyle therapy.

Goal for secondary prevention

Achieve LDL reduction of >=50% from baseline and a target goal of <55 mg/dL.

If goals not achieved on max tolerated statin

Addition of ezetimibe or a PCSK9 inhibitor with proven benefit is recommended.

For patients aged 40-75 years without ASCVD

Use moderate-intensity statin therapy in addition to lifestyle therapy.

For patients aged 40-75 years at higher CV risk (>=1 additional risk factor)

High-intensity statin therapy is recommended to reduce LDL by >=50% and reach goal <70 mg/dL.

For adults >75 years already on statin

It is reasonable to continue statin treatment.

For adults >75 years initiating statin

Consider initiating moderate-intensity statin after risk/benefit discussion.