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REVEAL Lite 2

Non-Invasive Monitoring • REVEAL Lite 2

Awaiting Follow-up Data

Guidelines & Evidence

Clinical Details

Section 1

When to Use

Follow-up Monitoring

Routine follow-up of patients with established WHO Group 1 PAH.
Monitoring treatment response without invasive hemodynamics (RHC).
Risk assessment at quarterly or bi-annual intervals.

When to Use

REVEAL Lite 2 is intended for follow-up assessments. Baseline risk stratification should ideally use the full 13-variable REVEAL 2.0 score incorporating Right Heart Catheterization.
Section 2

Formula & Logic

The 6 Non-Invasive Variables

VariableCriteriaPoints
NYHA/WHO FCClass III / Class IV+1 / +2
SBP< 110 mmHg+1
Heart Rate> 96 bpm+1
6MWD< 165 m+1
BNP / NT-proBNPBNP 200–799 / ≥ 800+1 / +2
Renal FunctioneGFR < 60 mL/min/1.73m²+1

Scoring Thresholds

Low RiskScore ≤ 5
Intermediate RiskScore 6–7
High RiskScore ≥ 8
Section 3

Pearls/Pitfalls

Validation Data

REVEAL Lite 2 has a C-statistic of 0.70. While slightly lower than the full 2.0 version (0.76), it provides reliable risk categorization purely through bedside assessment and standard labs.
Section 4

Evidence Appraisal

Primary Source

Development and Validation of an Abridged Version of the REVEAL 2.0 Risk Score Calculator, REVEAL Lite 2.

Benza RL et al. • Chest. 2021;

Last Comprehensive Review: 2026

Related Cardiovascular Tools

Martin/Hopkins LDL
Modified Duke Criteria
Modified Sgarbossa Criteria
MVA
Non-HDL Cholesterol
NT-proBNP Age-Adjusted Thresholds
ORBIT Score
Ottawa Heart Failure Risk
Pulse Pressure
PVR Calculator
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