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Acetaminophen Pediatric DoseAciclovir Pediatric DoseAmoxicillin Pediatric DoseAugmentin Pediatric DoseAzithromycin Pediatric DoseCaffeine Citrate LoadingCefalexin Pediatric DoseCeftriaxone Pediatric DoseClarithromycin Pediatric DoseDexamethasone Pediatric DoseFlucloxacillin Pediatric DoseFluconazole Pediatric DoseIbuprofen Pediatric DoseIndomethacin PDA ClosureMetronidazole Pediatric DoseNeonatal GentamicinNeonatal Phototherapy ThresholdNeonatal Seizure DosingNeonatal VancomycinNitrofurantoin Pediatric DoseOmeprazole Pediatric DoseOseltamivir Pediatric DosePediatric AdenosinePediatric AdrenalinePediatric AmiodaronePediatric AtropinePediatric Dehydration Fluid DeficitPediatric Fluid ResuscitationPediatric FlumazenilPediatric Gentamicin DosePediatric Glucose CorrectionPediatric LevetiracetamPediatric Maintenance FluidPediatric N-AcetylcysteinePediatric NaloxonePediatric Norepinephrine InfusionPediatric RSI Drug DosingPediatric Seizure DosingPediatric Vancomycin DosePrednisolone Pediatric DoseProstaglandin E1 InfusionSalbutamol Pediatric DoseSurfactant DoseTrimethoprim Pediatric DoseWeight Estimation
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Clinical Notice:OpiCalc is not a substitute for professional clinical judgment. Always verify dosages and guidelines.

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Recent Journal Updates

British J Clinical PharmacologyJun 26, 2026
Accelerating tacrolimus model‐informed precision dosing in kidney transplant recipients: Model evaluation and refinement strategies

Clinical Context

We think this might be relevant to the clinical guidance for Neonatal Seizure Dosing.

Clinical Pharmacology TherapeuticsJun 21, 2026
Ketamine Dosing Across Clinical Indications: A Narrative Review Organized by Proposed NMDA‐Related Mechanisms

Clinical Context

We think this might be relevant to the clinical guidance for Neonatal Seizure Dosing.

BJOGJun 11, 2026
Beyond the Seizure: Hidden Neurological Burden in Hypertensive Pregnancy

Clinical Context

We think this might be relevant to the clinical guidance for Neonatal Seizure Dosing.

Neonatal Seizure Dosing

ACUTENeonatal Anti-Epileptic Support

Dosing Inputs

Output Ready

Calculate loading and maintenance doses for common neonatal anti-epileptic drugs.

Guidelines & Evidence

Verified

Last Review: 2026

Dosing Guide

Phenobarbital (First-Line)
Loading Dose:20 mg/kg IV (over 20 mins).
Additional Load:May repeat 10–20 mg/kg if seizures persist (Max 40mg/kg total load).
Maintenance:3–5 mg/kg/day divided q12–24h (start 12h after loading).
Levetiracetam (Keppra)
Loading Dose:20–40 mg/kg IV (over 15 mins).
Maintenance:10–30 mg/kg per dose BID.
Phenytoin (Fosphenytoin)
Loading Dose:20 mg PE/kg (Phenytoin Equivalents) IV.
Monitoring:Monitor ECG and blood pressure during infusion.

Last Comprehensive Review: 2026

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