8,240 Clinical Drug Overviews
HYZYD
Comprehensive clinical and safety monograph for HYZYD (HYZYD).
Antitubercular (Isoniazid)
IBANDRONATE SODIUM
Calcium supplements and other oral medications can interfere with absorption Risk of esophageal irritation and osteonecrosis of the jaw.
Bisphosphonate
IBRANCE
Comprehensive clinical and safety monograph for IBRANCE (IBRANCE).
Cyclin-Dependent Kinase Inhibitor
IBRUTINIB
Strong CYP3A4 inhibitors may increase levels and inducers may decrease levels Can cause bleeding infections and atrial fibrillation.
BTK Inhibitor
IBSRELA
Comprehensive clinical and safety monograph for IBSRELA (IBSRELA).
Gastrointestinal Agent (NHE3 Inhibitor)
IBTROZI
Comprehensive clinical and safety monograph for IBTROZI (IBTROZI).
Nonsteroidal Anti-inflammatory Drug (NSAID)
IBU
Comprehensive clinical and safety monograph for IBU (IBU).
IBU-TAB
Comprehensive clinical and safety monograph for IBU-TAB (IBU-TAB).
IBU-TAB 200
Comprehensive clinical and safety monograph for IBU-TAB 200 (IBU-TAB 200).
IBUPRIN
Comprehensive clinical and safety monograph for IBUPRIN (IBUPRIN).
Ibuprofen
Avoid, especially after 20 weeks gestation. Associated with premature closure of the ductus arteriosus and fetal renal dysfunction leading to oligohydramnios. The FDA strengthened its warning in 2020 to include all NSAIDs from 20 weeks onward. Some studies suggest a modest increase in early miscarriage risk with first-trimester use, though evidence is not definitive.
NSAID
IBUPROFEN AND DIPHENHYDRAMINE CITRATE
ACE inhibitors and ARBs may have diminished antihypertensive effect Increases risk of serious cardiovascular thrombotic events and GI bleeding.
IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE
IBUPROFEN AND FAMOTIDINE
IBUPROFEN AND PHENYLEPHRINE HYDROCHLORIDE
IBUPROFEN AND PSEUDOEPHEDRINE HYDROCHLORIDE
MAOIs can cause hypertensive crisis Can cause insomnia and tachycardia.
Sympathomimetic
IBUPROFEN LYSINE
IBUPROFEN SODIUM
IBUPROHM
Comprehensive clinical and safety monograph for IBUPROHM (IBUPROHM).
IBUPROHM COLD AND SINUS
Comprehensive clinical and safety monograph for IBUPROHM COLD AND SINUS (IBUPROHM COLD AND SINUS).
NSAID/Decongestant Combination
IBUTILIDE FUMARATE
Other drugs that prolong the QT interval increase risk of torsades de pointes Can cause life-threatening ventricular arrhythmias particularly torsades de pointes.
Antiarrhythmic (Class III)
IC-GREEN
Comprehensive clinical and safety monograph for IC-GREEN (IC-GREEN).
Diagnostic Agent (Indocyanine Green)
ICATIBANT ACETATE
Comprehensive clinical and safety monograph for ICATIBANT ACETATE (ICATIBANT ACETATE).
Bradykinin B2 Receptor Antagonist
ICLEVIA
Comprehensive clinical and safety monograph for ICLEVIA (ICLEVIA).
LAMA/LABA Combination
ICLUSIG
Comprehensive clinical and safety monograph for ICLUSIG (ICLUSIG).
Tyrosine Kinase Inhibitor
ICOSAPENT ETHYL
Comprehensive clinical and safety monograph for ICOSAPENT ETHYL (ICOSAPENT ETHYL).
Antihypertriglyceridemic Agent
ICOTYDE
Comprehensive clinical and safety monograph for ICOTYDE (ICOTYDE).
ICS/LABA Combination
IDACIO
Comprehensive clinical and safety monograph for IDACIO (IDACIO).
TNF-Alpha Inhibitor
IDAMYCIN
Comprehensive clinical and safety monograph for IDAMYCIN (IDAMYCIN).
Anthracycline Antineoplastic
IDAMYCIN PFS
Comprehensive clinical and safety monograph for IDAMYCIN PFS (IDAMYCIN PFS).
IDARUBICIN HYDROCHLORIDE
Other cardiotoxic drugs (eg trastuzumab) increase risk Can cause severe and irreversible cardiotoxicity and myelosuppression.
Anthracycline Antibiotic
IDELALISIB
Comprehensive clinical and safety monograph for IDELALISIB (IDELALISIB).
PI3K Inhibitor
IDHIFA
Comprehensive clinical and safety monograph for IDHIFA (IDHIFA).
IDH2 Inhibitor
IDKIT:HP
Comprehensive clinical and safety monograph for IDKIT:HP (IDKIT:HP).
Diagnostic Test
IDOSE TR
Comprehensive clinical and safety monograph for IDOSE TR (IDOSE TR).
Drug Delivery System
IDVYNSO
Comprehensive clinical and safety monograph for IDVYNSO (IDVYNSO).
Antineoplastic Agent
IFEX
Comprehensive clinical and safety monograph for IFEX (IFEX).
Alkylating Agent
IFEX/MESNEX KIT
Comprehensive clinical and safety monograph for IFEX/MESNEX KIT (IFEX/MESNEX KIT).
Alkylating Agent with Uroprotective Agent
IFOSFAMIDE
Other bone marrow suppressants may have additive effects Can cause hemorrhagic cystitis (requires Mesna) and neurotoxicity.
IFOSFAMIDE/MESNA KIT
No significant drug interactions Used to prevent hemorrhagic cystitis caused by ifosfamide.
Uroprotectant
IGALMI
Comprehensive clinical and safety monograph for IGALMI (IGALMI).
Alpha-2 Adrenergic Agonist
IHEEZO
Comprehensive clinical and safety monograph for IHEEZO (IHEEZO).
Ophthalmic Corticosteroid
ILARIS
Comprehensive clinical and safety monograph for ILARIS (ILARIS).
Interleukin-1 Beta Inhibitor
ILEVRO
Comprehensive clinical and safety monograph for ILEVRO (ILEVRO).
Ophthalmic NSAID
ILLUCCIX
Comprehensive clinical and safety monograph for ILLUCCIX (ILLUCCIX).
Radiopharmaceutical Diagnostic Agent
ILOPERIDONE
Strong CYP2D6 or CYP3A4 inhibitors require dose adjustment Can cause orthostatic hypotension and QT prolongation.
Atypical Antipsychotic
ILOSONE
Comprehensive clinical and safety monograph for ILOSONE (ILOSONE).
Macrolide Antibiotic
ILOSONE SULFA
Comprehensive clinical and safety monograph for ILOSONE SULFA (ILOSONE SULFA).
Macrolide and Sulfonamide Antibiotic
ILOTYCIN
Comprehensive clinical and safety monograph for ILOTYCIN (ILOTYCIN).
ILOTYCIN GLUCEPTATE
Comprehensive clinical and safety monograph for ILOTYCIN GLUCEPTATE (ILOTYCIN GLUCEPTATE).
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