Sickle Cell Disease — Uganda (General Adult population)
Prophylaxis
Folic acid 5 mg once daily. Ensure good hydration and nutrition.
Painful Crisis (Mild)
Paracetamol 1 g every 6-8 hours or Ibuprofen 400 mg every 8 hours.
Painful Crisis (Severe)
Morphine 5-10 mg SC or IM every 4 hours or IV 2-5 mg every 1-4 hours.
Maintenance (Chronic)
Hydroxyurea 15-20 mg/kg once daily. Monitor blood counts.
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