Tuberculosis — Uganda (General Pediatric population)
First-Line Regimen (Susceptible TB)
Intensive phase: 2RHZE. Continuation phase: 4RH. (For all forms of TB excluding meningitis and bone TB).
Alternative 4-Month Regimen (Children 2mo-16yr non-severe)
Intensive: 2 HRE(Z). Continuation: 2RH. (H=Isoniazid, R=Rifampicin, E=Ethambutol, Z=Pyrazinamide).
Pediatric Dosing Reference
Isoniazid: 10 mg/kg (range 7-15). Rifampicin: 15 mg/kg (range 10-20). Pyrazinamide: 35 mg/kg (range 30-40). Ethambutol: 20 mg/kg (range 15-25).
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