Clinimix 5/10 sulfite free in dextrose 10% in plastic container
Clinical Indications
Parenteral nutrition for patients requiring caloric and protein support without additional electrolytes. Allows customized electrolyte additions.
Dosing & Administration Rate
Individualized based on nutritional requirements. Monitor blood glucose, fluid balance, and serum electrolytes daily.
Warnings & Precautions
High osmolarity requires central access. Monitor for refeeding syndrome in severely malnourished patients.
Contraindications
Known hypersensitivity to amino acids. Severe liver disease or hepatic coma. Severe renal impairment (without dialysis). Abnormalities of amino acid metabolism.
Pharmacology & Safety Profile
Mechanism of Action
Provides a source of biologically utilizable essential and non-essential amino acids for protein synthesis, and dextrose as a source of calories.
Adverse Reactions
Phlebitis, fluid overload, hyperglycemia, hyperosmolar syndrome, electrolyte imbalances, metabolic acidosis, liver enzyme elevations.
Compatibility Notes
Electrolytes and trace elements added per patient need. Check calcium-phosphate solubility curves.
Electrolyte & Composition Profile
| Component | Amount / Concentration |
|---|---|
| Amino Acids | 50 g/L (5%) |
| Dextrose (Anhydrous) | 100 g/L (10%) |
| Water for Injection | q.s. |
| Caloric Density | 340 kcal/L (from dextrose), 200 kcal/L (from protein) |
| Nitrogen Content | 8 g/L |
Clinical Parameters
Clinical Disclaimer: Data compiled from FDA DailyMed, Baxter/Fresenius prescribing information, and USP monographs. Always verify against the physical product label, your institution's IV protocols, and current pharmacist guidance before administration.
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