Clinimix 5/20 sulfite free in dextrose 20% in plastic container
Clinical Indications
High-calorie parenteral nutrition for patients with significant energy requirements and volume restriction.
Dosing & Administration Rate
Slow initiation to prevent severe hyperglycaemia. Monitor capillary blood glucose closely.
Warnings & Precautions
Extremely hypertonic. Central line placement verified before infusion. High risk of hyperglycaemia and osmotic diuresis.
Contraindications
Known hypersensitivity to amino acids. Severe liver disease or hepatic coma. Severe renal impairment (without dialysis). Abnormalities of amino acid metabolism.
Pharmacology & Safety Profile
Mechanism of Action
Provides a source of biologically utilizable essential and non-essential amino acids for protein synthesis, and dextrose as a source of calories.
Adverse Reactions
Phlebitis, fluid overload, hyperglycemia, hyperosmolar syndrome, electrolyte imbalances, metabolic acidosis, liver enzyme elevations.
Compatibility Notes
Custom electrolytes usually added by pharmacy.
Electrolyte & Composition Profile
| Component | Amount / Concentration |
|---|---|
| Amino Acids | 50 g/L (5%) |
| Dextrose (Anhydrous) | 200 g/L (20%) |
| Water for Injection | q.s. |
| Caloric Density | 680 kcal/L (from dextrose), 200 kcal/L (from protein) |
| Nitrogen Content | 8 g/L |
Clinical Parameters
Clinical Disclaimer: Data compiled from FDA DailyMed, Baxter/Fresenius prescribing information, and USP monographs. Always verify against the physical product label, your institution's IV protocols, and current pharmacist guidance before administration.
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