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Radiation Oncology

GPA Score (Graded Prognostic Assessment)

Prognostic Tool: GPA Index

Age (Years)

KPS (%)

Number of Brain Mets

Extracranial Metastases

Survival Estimator

Select clinical factors to estimate median survival and guide appropriate radiation strategy.

Guidelines & Evidence

Verified

Last Review: 2026

Prognostic Importance

What is the GPA?

The Graded Prognostic Assessment (GPA) is a simplified, user-friendly tool developed by the RTOG (Radiation Therapy Oncology Group) to estimate the survival of patients with brain metastases. It was designed to be more objective and quantitative than the older RPA (Recursive Partitioning Analysis). The original GPA uses four simple criteria: Age, Karnofsky Performance Status (KPS), number of brain metastases, and the presence of extracranial metastases.

The Scoring System (Original GPA)

Criteria	0 Points	0.5 Points	1.0 Point
Age (years)	> 60	50 – 60	< 50
KPS (%)	< 70	70 – 80	90 – 100
Number of Brain Mets	> 3	2 – 3	1
Extracranial Metastases	Present	N/A	None

Related Scores in Practice

In clinical practice, this assessment is frequently evaluated alongside other validated measures. Depending on the patient's presentation and specific diagnostic requirements, you may also need to utilize the Ds Gpa Index, Rpa Grading Brain Mets or the SRS Dose Selection (RTOG) to formulate a comprehensive care plan.

Last Comprehensive Review: 2026

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In Recent Clinical News

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