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ACMG/AMP Variant ClassifierAmsterdam Criteria IICYP2C19 Phenotype InterpreterDLCN Score (FH)GJB2 Variant InterpreterGhent-2 Criteria (Marfan)HTT CAG Repeat (Huntington)Hereditary Thrombophilia VTE RiskRevised Bethesda GuidelinesTyrer-Cuzick Breast Risk
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Recent Journal Updates

CancerJun 24, 2026
Magnetic resonance imaging radiomic phenotypes stratify response and define immune states in very high‐risk, nonmuscle–invasive bladder cancer treated with tislelizumab plus nanoparticle albumin‐bound paclitaxel

Clinical Context

We think this might be relevant to the clinical guidance for CYP 2 C 19 Phenotype Interpreter.

BJOGJun 22, 2026
Pre‐Eclampsia Beyond the Binary: Rethinking Phenotypes for Clinical Use

Clinical Context

We think this might be relevant to the clinical guidance for CYP 2 C 19 Phenotype Interpreter.

Clinical Pharmacology TherapeuticsJun 21, 2026
Ketamine Dosing Across Clinical Indications: A Narrative Review Organized by Proposed NMDA‐Related Mechanisms

Clinical Context

We think this has broad domain relevance to CYP 2 C 19 Phenotype Interpreter.

CYP2C19 Phenotype Interpreter

CYP2C19 Phenotype Interpreter

Translates CYP2C19 diplotype into actionable phenotype. Critical for clopidogrel (post-PCI), SSRIs, and PPIs. CPIC Level A recommendation for antiplatelet guidance.

Enter Diplotype from Report

— or select phenotype directly —

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

Translating CYP2C19 diplotype results from pharmacogenomic testing panels into actionable phenotype categories.
Guiding antiplatelet therapy selection after PCI/ACS — clopidogrel requires CYP2C19 activation.
Antidepressant and antipsychotic dosing guidance (SSRIs, TCAs, vortioxetine, citalopram).
PPIs dose optimisation (omeprazole, pantoprazole — CYP2C19 substrates).
CPIC (Clinical Pharmacogenomics Implementation Consortium) Level A recommendation for clopidogrel.

Last Comprehensive Review: 2026